🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Our review about evolution of sex - "the queen of all problems in evolutionary biology" through a microbial perspective was just published in PNASNews. Heitman lab at Duke #fungi #evolution pnas.org/doi/10.1073/pn… Hope you enjoy reading it!

A microbial perspective on the evolution of sex focussing on variations of sexual reproduction in #fungi is out now in PNASNews. This is the inaugural article by Joe, as a National Academy of Sciences member. pnas.org/doi/10.1073/pn…

Congratulations to Allan Jacobson and Lynne Maquat who received the 2023 Gruber Genetics Prize for landmark studies on nonsense mediated mRNA decay. Allan founded PTC Therapeutics which developed drugs used globally to treat human genetic diseases.

An updated version is now available for the study from @magwenelab, which uses the interaction between amoeba and human fungal pathogen Cryptococcus neoformans to test the “accidental pathogen” hypothesis. biorxiv.org/content/10.110…

Excited to share our new preprint on transitions in mating-type locus chromosomal organization in Malassezia and early steps in sexual reproduction biorxiv.org/content/10.110…. Kudos to @MarcoACoelho1, Giuseppe Ianiri and @MrciaDavidPalm1, and all authors, for their contributions.

Congratulations to two leading luminaries in fungal genetics, Amy Gladfelter and Regine Kahmann, on their recent election to the American Academy of Arts and Sciences!!! mgm.duke.edu/personnel/amy-… amacad.org/news/2023-memb…

Fungal Kingdom: Threats & Opportunities welcomes Asiya Gusa (@AsiyaGusa, Duke University), Kyla Ost (Kyla Ost, CU Anschutz Medical Campus) and Neta Shlezinger (Neta Shlezinger, Hebrew University). cifar.ca/cifarnews/2023…

Using surveillance data collected by the French National Reference Center for Invasive Mycoses and Antifungals, a recent report in mBio by the French Mycoses Study Group provides an updated comprehensive overview on the epidemiology of invasive fungal diseases (IFDs) in France.

While the overall incidence of major IFDs and their mortality rate remained relatively stable, the study observed increased fungemia in older population (mainly due to infections by C. albicans), as well as concurrent IFD infections.

The study highlights the importance of active surveillance of IFDs and the collaboration between mycologists and clinicians, calls for research on innovative approaches, include diagnostic tools and new antifungals, that can improve the global survival rates associated with IFDs.

We wrote a review on the importance of stress-responsive calcium-calcineurin signaling in fungal pathogens and how understanding this signaling cascade can be extremely fruitful. Read on - Calcineurin: The Achilles’ heel of fungal pathogens journals.plos.org/plospathogens/…

The latest PLOS Pathogens Pearls article by Vikas Yadav is now out. He reviews the essential roles of calcineurin in the virulence of #fungal pathogens of animals and plants and discusses what future studies should focus on to target this Achilles heel. journals.plos.org/plospathogens/…

🚨New Preprint🚨 Can signaling cascades modulate expression status even before turning genes on and off in the nucleus? We studied and found a direct role of calcium-responsive calcineurin signaling in RNAi at P-bodies, governing gene expression levels. biorxiv.org/content/10.110…

Check this out!

In the latest PNASNews , we discovered that RNAi-loss is more common than expected in the global population of Cryptococcus neoformans, driving distinct evolutionary paths: hypermutation via transposon accumulation or survival without hypermutation. pnas.org/doi/10.1073/pn…

Excited to share our new preprint on confirming the essentiality of four genes in mating-type locus in Cryptococcus neoformans! MYO2, although predicted to be essential, is dispensable for cell viability and important for cytokinesis and pathogenicity. biorxiv.org/content/10.110…