🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🥼 Janelia researchers led by Boaz Mohar (@[email protected]), Nelson Spruston, Luke Lavis & karel svoboda Allen Institute have developed a new imaging tool that maps brain-wide changes in neuronal connections. 🧠 🔗 janelia.org/news/new-imagi…

Mice raised in darkness (with intact circadian rhythms) develop: 📈 Insulin hypersecretion 📉 Impaired glucagon, gluconeogenesis & lipolysis ⚖️ Glucose intolerance & fat gain with age Light exposure is essential for metabolic health—even beyond the clock.

The human consciousness signal has been identified. Groundbreaking Science Magazine study convincingly showed that the activity of certain nuclei in the human thalamus are needed to consciously perceive what we see.

How microglia contribute to the induction and maintenance of neuropathic pain — a Review by Marzia Malcangio & George Sideris-Lampretsas nature.com/articles/s4158…

How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵

GABA imaging classifies amacrine cell types in mouse retina! Aki and Keisuke Yonehara are amazing! future goals include Gly imaging, 2-color Glu/GABA, more complete scRNA-seq/MERFISH mapped onto functional classes. Super-fun collaboration! Ilya Kolb Janelia GENIE

Psychiatric professionals tend to think that their expert judgment allows them to deliver diagnoses that are more confident than the diagnoses provided by simple statistical models. But they are wrong.

Mitochondria produce metabolites that shape cellular functions and behaviors The Mitochondrial Information Processing System (MIPS) is the cellular element that is best positioned to know what’s happening energetically and how the cell should be behave cell.com/action/showPdf…

Interesting weekend read: A series of studies published earlier this year suggests that birds & mammals did not inherit the neural pathways that generate intelligence from a common ancestor, but rather evolved them independently. quantamagazine.org/intelligence-e… ✍️ Yasemin Saplakoglu

Very happy that the long, long, long, long, long overdue day when the published results of all NIH funded research is immediately freely available to everyone who can benefit from it. Kudos to the NIH for making this happen, and eternal curses to the scientific societies,

Because they're not real majors. No "studies" field is built on authentic scholarly principles the way in which philosophy & history are. They were just made up majors invented to appease the radicals of the 1970s, & this is the predictable outcome x.com/data_depot/sta…

The brain decides if a movement belongs to you before you even make it. Fascinating Nature Communications study reveals that pre-movement alpha rhythms in motor cortex are not just preparatory, they’re the foundation of subjective control and sense of agency.

Cannabis smoking is linked with epigenome-wide disruptions which persist despite quitting. 🧵1/8

Arguably the biggest change in higher ed in my lifetime: IQs of humanities profs have crashed. Back in the 80s, even English professors, for all their flaws, were brilliant. I saw it with my own eyes.

"In adults, the brain makes up about 20 percent of the body's resting metabolic rate (calories burned when you're at rest); kids' brains burn through over 50 percent of their resting metabolic rate." a.co/d/fgTTAOv

organoids, while a powerful tool for studying human biology, lack immune systems, which is a significant limitation. NIH prioritized organoids to model human tissues and diseases in vitro. However, their lack of an immune system hinders their ability to fully recapitulate human

"involvement in activism was also related to higher levels of psychopathy...involvement in activism may provide opportunities for psychopaths to act sadistically (such as by publicly shaming political opponents) and also enjoy the violence they observe" a.co/d/eY8pTFT

It should be an absolute requirement of all NIH grants that all journals reviews - including/especially when they lead to rejection - should be made publicly available.