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Welcome back for Day 2 of the Beatson International Cancer Conference 2025! Kicking off today, we have Ke Yuan discussing self-supervised AI and how his group and collaborators are using it to map the landscape of histomorphological cancer phenotypes UofG Cancer Sciences #BICC2025

Continuing with the theme of AI, Fayyaz Minhas talked us through the promise and limitations of computational pathology deep learning models Fayyaz Minhas | University of Warwick | #BICC2025

Next up: short talks from Mark Jackson (University of Glasgow) looking at modification of the adverse effects of radiotherapy on the brain with DNA damage response inhibitors and Inge Jacobs (Department of Oncology - KU Leuven) who spoke about SPP1 macrophages and inflammatory signalling in CRC #BICC2025

Now time for some maths… Helen Byrne from Oxford Mathematics talked us through her work using maths to analyse tumour-immune interactions #BICC2025

Francesca Ciccarelli is up next to tell us about spatial drivers of response to immunotherapy in colon cancer Thank you to Transnetyx for sponsoring Francesca’s talk! Barts Cancer Institute (Queen Mary) | The Francis Crick Institute | CRUKCOLcentre | #BICC2025

Next we’re hearing from Britt van Abeelen from CRUK Scotland Inst about her work in the Miller and Bushell labs: a tRNA regulatory nexus of cell-state dependent protein expression UofG Cancer Sciences | #BICC2025

A fantastic keynote talk from Laura DeLong Wood about her lab’s exciting work with 3D multi-omic analysis of human pancreatic neoplasia Johns Hopkins Medicine | #BICC2025

For our final talk of the day, we’re hearing from Luciana Luque (CRUK Scotland Inst) about her work at The University of Edinburgh spatially profiling the tumour immune microenvironment in TNBC to reveal distinct tumour states associated with chemotherapy response #BICC2025

After a superb evening at our conference dinner and ceilidh, we’re back for the final day of #BICC2025 First up: Ram DasGupta presenting his lab’s work on mapping trajectories of therapy-induced tumour evolution in space and time Ramanuj Dasgupta | UofG Cancer Sciences

Next we have Edward Kaye from University of Dundee presenting on behalf of the Tony Ly lab on their work investigating the mechanisms that underpin cell proliferation-dormancy switches UoD Life Sciences | #BICC2025

The final talk of this morning’s session was given by Jernej Ule from King's College London Thanks to Transnetyx for sponsoring this talk! #BICC2025

Next up: Karuna Ganesh (Karuna Ganesh) discussing dissecting cancer plasticity during metastasis Memorial Sloan Kettering Cancer Center | #BICC2025

Our Lisa Duff speaking about her work using clinical FDG PET/CT to diagnose, predict and characterise metabolic changes in #cancercachexia at the wonderful #BICC. Her work is funded through Cancer Grand Challenges Challenges.

Another set of fantastic short talks from CRUK Scotland Inst’s Lisa Duff and Luis Pardo-Fernandez and Institute of Genetics and Cancer’s Jana Trávníčková #BICC2025

Kathryn Lilley (Kathryn Lilley) spoke about her work on cell wide protein localisation to understand therapy resistance mechanisms Cambridge Biochemistry | #BICC2025

Marco Fritzsche took us into the field of biophysics to tell us about the Fritzsche M et al work on new technologies to harvest the physics of T-cells to control the human immune response Rosalind Franklin Institute | Kennedy Institute of Rheumatology | #BICC2025

We have Ken Lau Lab closing this session, presenting his research on crypt stem cells and non-crypt cells in colorectal tumour initiation Vanderbilt School of Medicine | #BICC2025

We’re onto our final session of #BICC2025, kicking it off we have Raheleh Amirkhah (Raheleh Amirkhah) from Queen's University Belfast 🎓 who is researching intestinal zonation and it’s role in tumour initiation, evolution and progression in colorectal cancer #BICC2025

And now for our final speaker of #BICC2025: Rong Fan (Rong Fan) from Yale University who will be telling us about his spatial multi-omics work in lymphoma

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