🔬New paper from #WeTheFibrosisLab🔬Deciphering the Differences Between Stricturing With or Without Penetrating Crohn's Disease: One Step Closer to Solving the Puzzle ⁦Miguel Regueiro⁩ ⁦Fernando Magro⁩ ⁦Pranab Mukherjee⁩ ⁦Jyotsna Chandra, Ph.D.⁩ @ pubmed.ncbi.nlm.nih.gov/39074176/

Tim Raine Maria Manuela Estevinho Gabriele Dragoni Bram Verstockt Virginia Solitano Robin Dart Aline Charabaty, MD, FACG, AGAF #MondayNightIBD Joseph Sleiman, MD Beatriz Gros Vishal Sharma Anuraag Jena Dominik Bettenworth Seb Dr. Jalpa Devi Florian Rieder Gianluca Pellino Partha Pal alessandro armuzzi Robert Dudkowiak MD, PhD Lumír Kunovský Piotr Eder

Individuals that later developed #CD display a distinct & unique IgG Fc glycoprofile, characterized by an overall Fc agalactosylation of serum IgG1, IgG2 and IgG4 detectable up to 6y before diagnosis ➡️altered IgG Fc glycome signature positively correlated with presence of ASCA

MSCs-exosomes can promote macrophage M2 polarization via exosomal miR-21-5p through Mesenteric injection: a promising way to attenuate murine colitis Qian et al. academic.oup.com/ecco-jcc/advan…

Conclusion 1️⃣ 👇👇👇 #radiological imaging assessment showed: 🔴 stricturing complications in ➡️ 33.2% and 🔴 fistulizing complications in ➡️ 10.6% of patients with #CD. #MedEd #MedTwitter #Crohns Jan Král Seb Ana Dugic John Damianos, M.D. #UEGJ

A proinflammatory role for #eosinophils in colitis, warranting further investigation into eosinophil targeting as a treatment option for patients with #IBD. Inge Jacobs et al. Bram Verstockt Tim Vanuytsel Sara D Severine Vermeire academic.oup.com/ibdjournal/adv…

Stay tuned for more to come from #STARConsortium … We are immensely grateful to Helmsley Charitable Trust for the support of our work Miguel Regueiro Dominik Bettenworth Y-ECCO Fernando Gomollón Christina Ha MD Stefan Holubar MD MS Nature Reviews Gastroenterology & Hepatology Edward Loftus Uma Mahadevan Meena Bewtra Joseph Sleiman, MD

Thank you very much Helmsley Charitable Trust for supporting the #STARConsortium and for highlighting our recent consensus publication. 🙏Florian Rieder Y-ECCO alessandro armuzzi Fernando Magro Paulo G. Kotze Remo Panaccione, MD, FRCPC Taku Kobayashi Aline Charabaty, MD, FACG, AGAF Axel Dignass Maria Chaparro

🔴 Mild and severe side effects (odds ratio) associated with #probiotic intake in patients with #ulcerative #colitis and #Crohn's #disease 📕 only in UEGJ 🫠 👉tinyurl.com/y8f3akpy Paula Sousa Dominik Bettenworth #weareUEG #IBD #UEGEdu #myUEGcommunity 🟢

B cell academy of the gut: an update on gut associated germinal centre B cell dynamics DGKJ doi.org/10.1186/s40348…

Aleksejs Sazonovs Carl Anderson Tariq Ahmad Nick Kennedy Tariq Ahmad James Goodhand ExeterIBDresearch Simeng Lin Bram Verstockt Virginia Solitano Maria Manuela Estevinho Ruben Colman, MD, PhD alessandro armuzzi Dr Dermot McGovern Vipul Jairath MBChB DPhil Florian Rieder Dominik Bettenworth Florian Tran Beatriz Gros Charlie Lees Sang Hyoung Park

UEGJ Lumír Kunovský Fernando Magro Fernando Gomollón LT 👩🏼‍⚕️ 🥥🌴 Axel Dignass Dominik Bettenworth Florian Rieder Virginia Solitano Maria Manuela Estevinho Bram Verstockt Charlie Lees Seb alessandro armuzzi Beatriz Gros Piotr Eder Shrinivas Bishu Joseph Sleiman, MD Aline Charabaty, MD, FACG, AGAF John Damianos, M.D. Robert Dudkowiak MD, PhD

💥News from the #STARConsortium #WeTheFibrosisLab💥 Reliability of CT Enterography for Describing Fibrostenosing Crohn Disease | Radiology pubs.rsna.org/doi/10.1148/ra… - Important for Clinical Trial Endpoints in Stricturing Crohn’s disease Miguel Regueiro Christina Ha MD Meena Bewtra

Y-ECCO Excellent work by the authors #HannahGordon Uri Kopylov Bram Verstockt Maria Chaparro Tim Raine Javier P. Gisbert Dominik Bettenworth Raja Atreya Robert Battat MD Joline De Groof Taku Kobayashi GETECCU  Full text link👇 academic.oup.com/ecco-jcc/advan…

🔬MORE NEWS from #STARConsortium🔬After CTe now MRe🔬Reliability of MR Enterography Features for Describing Fibrostenosing Crohn Disease ⁦Radiology⁩ One additional step towards clinical trial endpoints for stricturing Crohn’s disease. pubs.rsna.org/doi/10.1148/ra…

Impact of Treatment Response on Risk of Serious Infections in Patients With Crohn’s Disease: Secondary Analysis of the PYRAMID Registry Reduced risk of serious infections with effective treatment CGH cghjournal.org/article/S1542-…

Vipul Jairath MBChB DPhil Julien Kirchgesner Natalia Queiroz Sophie Restellini Pascal Juillerat MD MSc, IBD specialist Tommaso Lorenzo Parigi Beatriz Gros guticas Fernando Magro Maria Chaparro Triana IBD Vishal Sharma Dr Yoon-Kyo An Uri Kopylov Dominik Bettenworth Manuel Barreiro Maria Jose Garcia Yamile Zabana pierre ellul Prof Richard Pollok

#GI #Derm Join us now for a convo led by Aline Charabaty, MD, FACG, AGAF 🎯How do you approach this #Derm disorder in #IBD 📸Posted w permission👇🏽 🗳️#IBDPoll👇🏽 💬Share your thoughts & expertise w us 🆓#CME👉🏽 bit.ly/MNIBD24-25 Support by edu grants AbbVie Takeda JanssenUS

Join us for a relevant topic for all #IBD experts led by Katie Falloon 👇🏽👇🏼👇🏻Miguel Regueiro Rita Rys Stefan Holubar MD MS Taha Qazi Suha Abushamma, MD Y-ECCO Dominik Bettenworth

The final frontier in #IBD? Disease prevention trials in IBD: feasibility to future outlook Nature Reviews Gastroenterology & Hepatology pubmed.ncbi.nlm.nih.gov/39304774/ clinicaltrials.gov/study/NCT05211… clinicaltrials.gov/study/NCT05566… clinicaltrials.gov/study/NCT03950… Laurent Peyrin-Biroulet Silvio Danese Fernando Gomollón