New paper up on Eartharxiv with A. eartharxiv.org/repository/vie…

Pleased to share our latest review article on "Evolution of β-lactamases and enzyme promiscuity" in PEDS, PEDS: Protein Engineering, Design & Selection. We discussed evolutionary origins of six independent evolution of β-lactamases - a fascinating convergent evolution example. doi.org/10.1093/protei…

Israeli archaeologists find whole 1,000-year-old egg – and accidentally break it haaretz.com/archaeology/.p…

Check out our review with Rita Osadchy that just came out at The Journal of Physical Chemistry: How Deep Learning Tools Can Help Protein Engineers Find Good Sequences. Deep learning, protein engineering, generative models, what more can you ask :) pubs.acs.org/doi/abs/10.102…

Our latest paper "The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis" is out Nature Communications: nature.com/articles/s4146….

New paper from the lab online Nature Communications When do antioxidants evolve in Cyanobacteria? Also superoxide dismutase enzymes (SODs) containing Ni evolved when cyanobacteria colonised the open ocean. Joanne Boden nature.com/articles/s4146…

One of the last papers I worked on with Danny Tawfik before his passing, a deep dive into the evolutionary history of the HUP protein lineage. doi.org/10.1080/104092…

A beautifully written piece. Thank you guys, it really touched me.

Dan Salah Tawfik (1955–2021) | Nature Chemical Biology nature.com/articles/s4158…

Levels of pollutants are increasing so fast that they have become a good source of food for marine bacteria! New study from the Tawfik lab in collaboration with Einat Segev on organophosphate utilization. biorxiv.org/content/10.110…

Now out in Nature Chemical Biology! nature.com/articles/s4158… Missing Danny (Prof. Dan Tawfik) a lot. Special thanks to Jamie James Fraser (A$AP J) for being a pillar of support during this hard time. #Bacillus #enzymes #CryoEM #metabolism

The Feinberg Graduate School invites #undergraduate, #graduate students, and #postdoc researchers to apply to our supported Visiting Students Program for #Ukrainians: 5K NIS per month up to 6 months + accommodation + airfare. For more info 👉 bit.ly/3HNofdw #ukraine

Evidence for early statistical translation AND a new paradigm for AARS evolution we call "generalist maintaining" - check out our latest manuscript here: biorxiv.org/content/10.110…

Queen Elizabeth reigned over both Alan Turing and the GPU.

Danny was inspired by phosphate binding loops (PBLs), which are some of the most ancient structures in biology. For the Protein Science issue in his honor, Hayate Hirai and I took a look at a lesser-known PBL that lies at the heart of Nat/Ivy proteins. onlinelibrary.wiley.com/doi/abs/10.100…

The Ancient Protein Saga Continues -- Our New Manuscript on the functional ambidexterity of an ancient domain is now available. Liam M. Longo The Metanis Group