Congrats James! Exciting for the whole cGAS-STING field to see this discovery honored. (and fun to be able to write this little piece for the NEJM)

Prof Dr Kevin Fong giving the most devastating and moving testimony to the Covid Inquiry of visiting hospital intensive care units at the height of the second wave in late Dec 2020. The unimaginable scale of death, the trauma, the loss of hope. Please watch this 2min clip.

Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213 doi.org/10.1101/2024.0…

Join the RNA Virus Replication Lab The Crick, Europe's largest biomedical institute under 1 roof! 🔴 TWO postdocs (4-6yrs) 🔴 ONE PhD student (4yrs, fully funded, all🌍) We’re looking for bright, motivated people, with the chance to develop & shape projects independently... 1/n

PhD applications are open The Crick If you are interested in the actin cytoskeleton and🔬then check out my labs project on Arp2/3 iso-complexes and invadopodia. Please RT 📡 crick.ac.uk/wayphd25

Incredible opportunities here The Crick for clinicians to undertake a fully funded PhD – similar to (or better than) obtaining MRC fellowship. crick.ac.uk/careers-study/…

PhD position available in my lab to study this further! crick.ac.uk/careers-study/…

A vaccine has essentially eliminated a dreadful form of cancer. Extraordinary.

We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme 🔬🩺 Projects are available with UCL, King's College London and Imperial College London 🗓️ Apply by 15 November 2024 crick.ac.uk/careers-study/…

Zoom into the #flywire fly brain courtesy of another of Philipp Schlegel's (Fly Connectome Dept of Zoology MRC Laboratory of Molecular Biology) amazing 3D sequences. Then read his piece on the flyconnecto.me blog to find out more about how the #connectome became a reality flyconnecto.me/2024/10/02/fly….

I made my BBC documentary Better Off Dead? to explain why me & many other disabled people oppose legalising assisted suicide. Some of us have very real fears based on our lived experience & based on what has happened in other countries where it's legal. bbc.co.uk/iplayer/episod…

THIS. I am beyond "highly sceptical", I think it's not remotely feasible. Any competent government with a real grip on policy would not even be contemplating this kind of legislation.

*Alarm bells*

Really excellent interview on Today programme just now with palliative care specialist on the issues with the assisted dying proposals on the table. Pleased we are now having more nuanced conversations in the media about the serious risks.

But what if the suffering that drives some people into finding life unbearable is avoidable, unnecessary suffering? Suffering that could & would be alleviated - if only UK palliative care services weren’t a threadbare patchwork of appallingly underfunded inadequacy? 1/3

PhD opportunity for a clinician in my lab! Co-supervised by Mike Devine crick.ac.uk/careers-study/…

RNF213 ubiquitylates LPS but also restricts LPS-free pathogens: bacteria, parasites and viruses! Is RNF213 an amazingly versatile pattern-recognition receptor (#PRR) or does it act downstream of specific PRRs? The answer hot from the EMBO Reports press: embopress.org/doi/full/10.10…

The 2024 #NobelPrize laureates in chemistry Demis Hassabis and John Jumper have successfully utilised artificial intelligence to predict the structure of almost all known proteins. In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have

embargo email just dropped! being in the know one day early's one of the real highlights of being a bookseller