🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

I am excited to announce that in March, I will start my lab in the Department of Cancer Biology (Univ. of Pennsylvania Department of Cancer Biology) at the University of Pennsylvania Perelman School of Medicine (Penn Medicine). Stevens.bio

Excited to see our work published in Science Magazine on generating novel disordered proteins with PLMs that selectively localize in biomolecular condensates! An honor to collaborate with Peter G Mikhael Ilan Mitnikov Henry Kilgore Regina Barzilay Richard Young science.org/doi/10.1126/sc…

This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research? All of them.

Imagine running a restaurant & suddenly only having budget for ingredients & chefs—no rent, electricity, heat, water, support staff, insurance, trash, toilet paper. This is what 'cutting indirects' did to every major biomedical center & hospital in the US.

NEW POST on NIH indirect costs, why last night's action is illegal, and how to actually improve research efficiency! goodscience.substack.com/p/indirect-cos…

Congrats to outstanding postdoc Jing Li on leading the newest paper from the lab with the amazing support from collaborators at Rice, UNC-CH, and Duke. We show that aberrant IDR fusions can provoke oncogenic gene expression via distinct engagement patterns with the human genome.

New research in Science represents a notable step forward in designing enzymes from scratch. With a new approach, researchers designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, analogous to what many proteases do when breaking apart proteins.

Rice bioengineer Gang Bao and collaborators at Baylor College of Medicine have developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver. bit.ly/4gAHOaA

Join us February 20 for a Bioengineering Colloquium featuring Dr. Carl de’Boer from the University of British Columbia. He will share insights to his research on continual improvement of cis-regulatory models. bit.ly/41fMmif

So we beat on. Gene/cell therapies often use proteins that could be recognized/rejected as non-self by our immune system. We combine algorithms to build proteins that are therapeutically relevant and can masquerade as our own parts doi.org/10.1101/2025.0…

Rice Innovation announced its most recent awardee of the One Small Step Grant: RICE BIOENGINEERING NSF Graduate Research Fellow AJ Walters. Funding supports his therapeutics solution company Chassis.Bio, which develops tech to target neuroinflammation. news.rice.edu/news/2025/rice…

Bio-based production of poly(ester amide) for the first time. Great work, Dr. Chae and co-authors. Biosynthesis of poly(ester amide)s in engineered Escherichia coli Nature Chemical Biology rdcu.be/edUDv nature.com/articles/s4158…

Fresh in Nature Biotechnology! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with Chappell Lab & Joff Silberg and incredible students. nature.com/articles/s4158…

Information storage across a microbial community using universal RNA barcoding go.nature.com/440gL5E

Protein function often depends on protein dynamics. To design proteins that function like natural ones, how do we predict their dynamics? Hannah Wayment-Steele and I are thrilled to share the first big, experimental datasets on protein dynamics and our new model: Dyna-1! 🧵

Unlike a lot of other universities right now, we are still hiring for new faculty here at Imperial in London 🎉🚨🇬🇧🫖 If you want to come and run a research group in the theme of bioengineering then apply to be my colleague before the end of April. imperial.ac.uk/jobs/search-jo…

Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo go.nature.com/4kFUnEO

Thrilled to share our preprint led by Xinyi Chen on programmable molecule delivery via engineered trogocytosis called TRANSFER! a 🧵 Sarafan ChEM-H Stanford Bioengineering

Happy Sunday to all! This morning, we are excited to share Chase’s work developing a simple, scalable method to assemble 100s-1000s of custom genes from oligo pools using standard lab tools! (Small 🧵 below)

🚨 Our lab just rewrote life‘s operating system! Together, we’ve built Syn57 - an E. coli with a synthetic genome running on a 57-codon genetic code! biorxiv.org/content/10.110… #SyntheticBiology #Syn57 #PhD #GeneticCode #GenomeEngineering #Biosecurity #FutureOfBiology