Fascinating discovery by @Annaglobig! Exhausted CD8 T cells talk to sympathetic nerves in tissues & tumors. Tex cells express ADRB1 and localize near sympathetic nerves, listening to stress hormone noradrenaline. This promotes their dysfunction. nature.com/articles/s4158…

Check out @KentLangston’s recently published work on muscle Tregs and their role in exercise. Fascinating read that shows a role for Tregs in improving exercise performance!

Congratulations Diane! What an inspiring career!

✨#ImmuneDictionary✨is out today in nature! Paper nature.com/articles/s4158… Software immune-dictionary.org We created scRNA-seq dictionary of 17+ immune cell types responding to 86 cytokines in vivo, discovered the immune system is far more complex than previously known 1/

Check out Silvia’s beautiful paper on how immune cells from the gut migrate through the body!

Lab manager / staff scientist for not one, but TWO of the coolest Systems Immunology labs at Pitt?! It is possible. @alokjoglekar and I have a joint search. Please DM or email to apply or get more information.

Really looking forward!

What a PERFFect day to share our new preprint! With Tsion Abay #BobStickels Meril Takizawa @ChaligneRonan and Ansu Satpathy, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. biorxiv.org/content/10.110… 1/n

At long last published! Skeletal muscle regeneration in 3 dimensions! Thanks to Dr. Brittany Collins Jake Shapiro Mya Scheib Rob Musci @Mayank_Verma_ #myotwitter Developmental Cell cell.com/developmental-…

CBDM lab checking out the eclipse!

Congratulations Sue! Extremely well deserved! You’re an inspiration to us all!

Congrats! Can’t wait to see the amazing work from your lab!

Check out this beautiful story on meningeal Tregs by a rockstar student in Diane’s lab!

Beyond excited to share our #NewPaper in Cell! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…