More tension sensors! pubs.acs.org/doi/10.1021/ac…

#Postdoc Opportunity: Do you love #mechanobiology, #microscopy, and #cellmigration? Join our team at Cornell BME and Weill Institute for Cell & Molecular Biology to investigate how cells squeeze their nucleus through tight spaces and how this affects nuclear structure and function. tinyurl.com/mechanobiology…

Since long time we tried to achieve “permanent” labelling of plasma membranes. Now it become possible with MemGraft probes, which exploit a new principle of lipid-directed covalent fluorescent labeling of membrane proteins. The MemGraft probes are compatible with fixation,

"Flipper-TR reveals the secrets behind membrane tension gradients."... Check out my latest preLights post 👇covering the latest bioRxiv from the team of Roux Lab with the first author's response Juanma García-Arcos. prelights.biologists.com/highlights/act… .

It took more than a DECADE... but finally it’s published!!! It started as a CRAZY idea but after tons of hard work we built it: We hijacked the endogenous secretion systems of Toxoplasma gondii, a brain parasite, to deliver active proteins to neurons 👇 nature.com/articles/s4156…

A paper in Nature Neuroscience presents a suite of genetically encoded opioid peptide sensors for probing opioid drugs and brain-region/circuit-specific opioid release in behaving animals. go.nature.com/4bJ2j2d

All of this mechanical reprogramming is still captivating pubs.acs.org/doi/10.1021/ac…

📢 Do cells migrating on a confined environment have a mechanical memory of their previous state ? We tried to answer this question in our new preprint 👇🏼 biorxiv.org/cgi/content/sh… an outstanding work by Kalukula Yohalie and very great collab with David Brückner

Mathieu, M., Isomursu, A., & Ivaska, J. (2024). Positive and negative durotaxis – mechanisms and emerging concepts. Journal of Cell Science, 137(8), jcs261919. #EpithelialMechanicsReview doi.org/10.1242/jcs.26…

SNAP-tag2: faster and brighter protein labeling biorxiv.org/content/10.110…

I added image-generation capabilities to the ipy-llm-kernel so you can use #DALLE3 within Jupyter. I hope it's useful, e.g. for crafting prompt-engineering training materials. 🌴🏝️ github.com/haesleinhuepf/…

Are you interested in the proteins that enable macrophages to eat, kill, and digest bacteria, apoptotic cells, or other debris? Here, we present PhagoID, phagosome proximity labeling we used to profile human and mouse phagosomes with quantitative mass spec! (1/ 11)

Introducing #NovaFLIM: our new #fluorescence lifetime imaging analysis software. It is designed for an efficient and multi-faceted analysis of #FLIM, FLIM-FRET, and #anisotropy. ➡ Learn more: picoquant.com/products/categ…

WHaloCaMP is a chemigenetic calcium indicator based on HaloTag that can be combined with different rhodamine dyes for multiplexed or FLIM imaging in vivo, as demonstrated in neuronal cultures, brain slices, Drosophila, zebrafish larvae and mouse brain. nature.com/articles/s4159…

Brooks, J. W., Tillu, V., Eckert, J., Verma, S., ..., Parton, R. G., & Yap, A. S. (2023). Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience. Molecular biology of the cell, 34(12), ar120. #EpithelialMechanics molbiolcell.org/doi/10.1091/mb…

The NIH's research integrity scandal involving neuroscience chief and #Alzheimer’s/#Parkinson’s scientist Eliezer Masliah is of an extraordinary scale. It might be useful to follow one thread of the investigation involving the experimental drug prasinezumab from Prothena Corporation.

Shellard, A., & Mayor, R. (2021). Collective durotaxis along a self-generated stiffness gradient in vivo. Nature, 600(7890), 690–694. #EpithelialMechanics nature.com/articles/s4158…

How can you take your data one important step closer to #FAIRdata 🤔? Check out #EuroBioImaging's FAIR image data decision tree🌳- designed to guide you in the selection of appropriate repositories. Separate trees exist for different image data types! Check it out⤵️

We are building a quantitative imaging team University of Warwick BioMedSci Warwick ‼️3 postdoc positions open‼️ Join an interdisciplinary endeavor with Masanori Mishima Jitu Mayor Lab MohanBalasubramanian on a Wellcome funded project to push probe and microscopy development: warwick-careers.tal.net/vx/lang-en-GB/…

How does nano-scale plasma membrane structure underpin tissue development? Let’s find out! First opportunity to do a PhD with me, co-supervised by Darius Koester, at Warwick Fully funded studentship by #MIBTP and University of Warwick More info here: findaphd.com/phds/project/p…