The reality is we could've easily mastered energy, food, and material abundance with 1970s era Technology. Instead, we loaded up on virtue signaling, stakeholder engagement, and regulatory capture. I call this general phenomenon "The Blight"

When Haniyeh was assassinated there were screeches condemning Israel because of how this might impact ceasefire negotiations. There isn’t a word from these same people about how Hamas murdering six innocent civilian hostages will impact these negotiations. How interesting.

"Ozempic only works while you're on it! Once you go off you'll be fat again!" As opposed to diet and exercise, which you only have to do once.

Are you an undergrad, early PhD student, or new grad interested in longevity? If so, we'd like to know how good you are at ping pong! Carol and I are hosting an age1 office ping pong tournament next Monday starting at 5:30pm. Be there or be square! lu.ma/az81bh82

“I thought to myself that if this was how I was being treated as a Muslim, how were the Jews being treated?” The harrowing account from rescued hostage Farhan al-Qadi. On October 7, al-Qadi was working on an Israeli kibbutz. Terrorists caught him and after demanding proof that

You know what's cooler than taxing unrealized gains? A completed DoD audit. This will sound crazy, but I propose we do the very basics and get the government to spend less than it brings in first before we start figuring out how to tax imaginary money.

Humans are actually extremely cool and we are probably still at the beginning of our story.

we should put air purifiers in literally every building

Ozempic but for needing less sleep. Who’s building this

Is it just me or has science twitter largely disappeared now? Used to scroll through and compulsively open a dozen papers, now its one or two and mostly just AI

The inventor of liraglutide (one of the earlier GLP-1 drugs, like Ozempic) wrote a great history of its development. Many metascience gems on how mouse studies can both guide & mislead, the very long timelines in drug development, etc. [notes below]

The brilliant Saul has Gone to mastodon has snagged a very well-deserved Ig Nobel Prize for debunking fraudulent claims of extreme longevity! Congratulations! #BlueZones #longevity

Investors always want to know how your idea is defensible. The truth? There is rarely defensibility. There is only speed.

Life update! I’ve joined the Amaranth Foundation as a NeuroAI researcher. I'll work on an ambitious roadmap for neuroscience for AI safety 🎉 1/ amaranth.foundation

How to Build the Virtual Cell with Artificial Intelligence: Excited to share our vision of how to build foundation models for molecules, cells, and entire tissues. Our Universal Cell Embedding (UCE) model is the first in this series and we are going to release more models in the

Nature research paper: Pathogenic hypothalamic extracellular matrix promotes metabolic disease go.nature.com/3MTvkyc

Also obsessed. The field of longevity/aging has not properly reckoned with these findings at all. it fundamentally calls into question all research on centenarian populations, a massive deal.

Some evidence for what everyone suspected: (Some) authors don't want to share data because they don't want people to see how the sausage was made journals.plos.org/plosone/articl…