🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The Cabinet has approved the ‘Bio-RIDE’ scheme, which will further support India's strides in biotechnology. Emphasis will be given to innovation, funding and capacity building. This scheme will also encourage sustainable development. pib.gov.in/PressReleasePa…

We are thrilled to announce one day conference on #metabolic disorders. We are looking forward to the talks from clinicians, academicians and startups. Stay tuned for more information. Mehta Family Center for Engineering in Medicine IIT Kanpur Shekhar Mande

Mitochondria crawling on the nuclear membrane. Live imaging at x100,000 magnification by Liangyi Chen

Thrilled to put this super exciting story, on GPR155, together with Appu Kumar Singh, Mansi Sharma and rest of the twitterless team members. Thanks to DBT-THSTI and SERB (#ANRF) for funding and support

Thanks much Shikha, it is again a spectacular collaboration and a great working with you

Cryo-EM structures of human GPR155 elucidate its regulatory and transport mechanisms | bioRxiv biorxiv.org/content/10.110…

VirtualIce: Half-synthetic CryoEM Micrograph Generator biorxiv.org/cgi/content/sh… #biorxiv_molbio

LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR disq.us/t/4qyvzo7

Nature research paper: Whole-brain annotation and multi-connectome cell typing of Drosophila go.nature.com/4dNAkjf

Our latest cryo-EM study, elucidating the type 3 Ryanodine Receptor (RyR3) in different conformational states nature.com/articles/s4146… Unexpected binding sites for ATP and chloride in the N-terminal region, affected by mutations linked to epileptic encephalopathy.

Happy to share our latest work, now on BioRxiv! Here, we determined the cryo-EM structure of the yeast SEAC (GATOR)-EGOC (Ragulator-Rag) supercomplex, providing new insights into the function of this amino acid-sensing hub. biorxiv.org/content/10.110…

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

The #BioE3 policy is fueling bio-innovation across Bharat, focusing on the economy, environment, and employment. A tech-driven India has the potential to break the middle-income trap, with R&D as a cornerstone of growth. The twin tech transitions -digital and green technologies -

I’m excited to share our latest preprint, where we showcase the development of two computational tools to facilitate the analysis of highly heterogeneous cryo-EM datasets. (1/7) biorxiv.org/content/10.110…

Meet The Shielded Plasmid🛡️🧬 Our new nature paper reveals how plasmids outsmart bacterial defenses during conjugation. It's all about being in the right place at the right time! The positioning of anti-defense genes boosts transfer efficiency🧵(1/7) nature.com/articles/s4158…

A massive team effort, “Cryo-EM of native membranes reveals an intimate connection between the Krebs cycle and respiration in mycobacteria.” Cryo-EM methods AND fundamental insight into mycobacterial metabolism, which is a target for TB drugs! 🧵 biorxiv.org/content/10.110…

Happy to see this out in its final form. Tanja and Clémence show how intracellular immune effectors form coats on gram-negative membranes to encapsulate cytosol-invasive bacteria: nature.com/articles/s4159…

Beautiful it is, congratulations