🎉 Exciting news! Our lab's first publication in Genome Biology is out now! We've delved into the large-scale genomic differences between T2T-CHM13 and GRCh38, shedding light on their association with neurogenic disorders & the evolutionary history of the KLRC gene cluster. 🧬

Many thanks to those who made this work possible! Mitchell R. Vollger Nae-Chyun Chen Dylan Taylor, William Harvey Glennis Logsdon Rajiv McCoy Michael Schatz Evan Eichler EichlerLab Genome Biology Special thanks to my team (Xiangyu & Xuankai & others)! genomebiology.biomedcentral.com/articles/10.11…

I'm absolutely thrilled to share that I will be joining Penn Genetics and Penn Epigenetics as an Assistant Professor in January 2024! My lab will investigate centromere variation/evolution and its impact on health & disease using long-read sequencing! Reach out if you'd like to join!

Super excited to announce our new VGP-ERGA-Galaxy pipeline for scalable, accessible, and reproducible reference genome assembly. In just a few clicks anyone anywhere can assemble their genome to VGP quality! Vertebrate Genomes Project (VGP) g European Reference Genome Atlas biorxiv.org/content/10.110…

Amazingly, we offer this capability completely for free in Galaxy so that all labs, big and small, can take advantage of it. Within VGP, we look forward to working together to assemble all 70k vertebrate species! Tutorials and workflows are available here: galaxyproject.org/projects/vgp/

Our new minimizer-space HiFi-read mapper, mapquik, is now published online (as an advance article) in Genome Research! genome.cshlp.org/cgi/content/lo… The recording for the RECOMB 2023 talk is also now up: youtu.be/ZXZSCDzVp3A

Promising new metagenome assembler for HiFi data by Gaetan Benoit

My username is not available on Instagram/Threads :( that might be the highest switching cost I've encountered so far

🧵 on new minimizer-space metagenome assembler metaMDBG 👇

I would like to welcome Jen Troyer, Ph.D., in her new role as incoming Director of NHGRI’s Division of Extramural Operations. For years, Bettie Graham, Ph.D. – a legend NIH and beyond! – has served in this position; she will be outgoing Director until she retires in late 2023.

Major, fatal errors found in the data and methods of a 2020 paper in nature, including millions of reads mis-identified as bacteria. The "cancer microbiome" in this study was simply not there. @abrahamgihawi Mihaela Pertea Yuchen Ge Jen Lu biorxiv.org/content/10.110…

This year BG23 has an Academy! Come learn how to use that software you tried alone but had many questions! Led by experts and developers on BlobToolKit, BUSCO, EarlGrey, EASEL, EBI Data Portals, ENA Submissions, Ensembl Annotation, Gfastar, GoaT, hifiasm, Merqury, MitoHiFi, +

NCBI Comparative Genome Viewer, NCBI Datasets, Nextflow, Smudgeplots, Treeval, VGP Galaxy Pipeline! 27 sessions already scheduled across time zones FREE and OPEN-TO-ALL Over 310 spaces already booked, so sign up ASAP at BGA23.org/sessions

Distinguished Univ. of Maryland Professor Rita Colwell made Forbes' "50 over 50" list of women changing the world through innovation. A renowned microbiologist for her work to eradicate diseases, Colwell also founded a tech company that analyzes microbiomes. forbes.com/50over50/innov…

I'm so proud of the IndigiData initiative. Since starting two summers ago, this workshop has skyrocketed to create timely and much-needed informatics and Indigenous data science workshops on topic areas of direct impact to Tribal Nations. Ahéhée' to everyone who make it happen!

🚀 Unleash the need for speed with the sizzling hot Mashtree v1.4 update! ⚡️ Experience the thrill of faster performance as we bid adieu to the sqlite dependency and usher in a sleeker codebase. 📦Share your thoughts on GitHub issues. ✨💻 Update now: github.com/lskatz/mashtree 🌐

We’re looking for a new Head of Research. Join us to lead, inspire, and shape the future of bioinformatics Closing: 2 Oct 2023

New video from Front Street shows virtually all of downtown Lahaina has been burned down.

Thrilled to share my first paper on GWAS! 📚🧬We utilized imputed genotypes through a new Asian population panel we established, and integrated GWAS with snATAC data to uncover causal cell types! 🧬🧪 Published in Science Advances today! 🎉🥳🥳 doi.org/10.1126/sciadv…

Extra-long tandem repeats (ETRs) such as centromeres and immunoglobulin loci are difficult to align. UniAligner is a computational method for efficiently and accurately aligning ETRs, facilitating analysis of their variation and evolution. Andrey Bzikadze nature.com/articles/s4159…