One final thing. Harvard has launched an incredible effort to share the impact of the funding cuts with the public on their website landing page. We need more like this: harvard.edu

Without its international students, Harvard is not Harvard. hrvd.me/IntStudents25t

A lot is happening, but science keeps me excited and energized. This is how much we scientists care about discovery and making a positive impact on society. Thank you to everyone who supports us.

Listen to David R. Liu explain why it is so important to support basic science

Wait whaaaat! So excited to combine ChimeraX and Boltz!

Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀

Thank you everyone for attending the Boltz-2 Boston, San Francisco and Paris events this week! Given the success of the in-person seminars and the many requests, we are organizing a virtual seminar on Tuesday at 12pm ET / 6pm CET! Sign up here: lu.ma/4bpuwbsr

We aim to recognise postdocs/early career researchers who are 💫 rising stars 🌟in bioengineering! Nominate someone or nominate yourself! Deadline is in a few days!

This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) Nature Chemistry nature.com/articles/s4155… nature.com/articles/s4155…

Here Is All the Science at Risk Harvard University— including several of our own research grants. nytimes.com/interactive/20…

Excited to share #AlphaGenome, a start of our AlphaGenome named journey to decipher the regulatory genome! The model matches or exceeds top-performing external models on 24 out of 26 variant evaluations, across a wide range of biological modalities.1/6

So cool, a novel archaeon with a super small genome and no metabolic genes! "An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses." biorxiv.org/content/10.110…

New Preprint Out from the Molinari Lab! We’re thrilled to share our latest work on engineered living materials in collaboration with Prof. Lorenzo Pasotti and Paolo Magni🇮🇹 biorxiv.org/cgi/content/sh… #SyntheticBiology #EngineeredLivingMaterials #ELMs #Biomanufacturing

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

Light-up nanostructures with allosteric DNA mimics of GFP doi.org/10.1101/2025.0…

Synbio will take off when we realize that bioreactors are the problem. Releasing organisms to solve environmental problems is where the action is and will be. Leverage biology's ability to replicate.

After a long sleep, environmental remediation with live biologics is back to the mainstream R&D agenda at this side of the pond. Wanna join an EU-wide on line conversation with bioremediation stakeholders this Nov 10? Express interest and register here 👉 forms.cloud.microsoft/e/b7xVz7dJcu

ChimeraX daily builds can predict binding affinity of small molecules using Boltz 2 on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…

As a biologist, I've tried many Electronic Lab Notebooks and never found true love It could be the inherent complexity and messiness of biology. Or it could be that all creative work is hard to document Curious if software people see note-taking as a (mostly) solved problem?

Out of our lab’s four sophomore undergrads from two summers ago, three are now married and one just got engaged. It’s striking how quickly young scientists are building families, despite academia rarely making room for that. The only woman in the group already stepped away from