Amyloid strengthens synaptic connections between regions loaded with neurofibrillary tangles, fueling the propagation of tauopathy in AD. Universität München ow.ly/Ynzo50UMfg7

Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease | Science Translational Medicine science.org/doi/10.1126/sc…

What’s the relationship between #AmyloidBeta and tau protein? New research involving #AlzheimersDisease patient PET and fMRI data reveals amyloid-beta may drive tau spread through hyperconnectivity between vulnerable brain regions. Nico Franzmeier Sebastian Roemer-Cassiano scim.ag/3CfY6aR

The results from the "Exenatide-3" Phase 3 clinical trial of the diabetes drug bydureon in 194 people with #Parkinsons (2yrs treatment) have been published; Safe & well tolerated, but "no evidence to support exenatide as a disease-modifying treatment" thelancet.com/journals/lance…

Please, share!

Pls RT 🤩🎉Fantastic launch of the #Parkinsons #MOOC this week 👏 ✅4,000 people from >30 countries have completed it in the first 3 days! Grab your📲 or 💻 and join this video-based interactive course to see why it’s getting rave reviews! ⭐️⭐️⭐️⭐️⭐️ mooc.utas.edu.au/course/20278

Open #Postdoc position @isd_research Universität München to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international Foundation Leducq Network of Excellence brenda-leducq.de. Experience in vascular biology or related field required. Please RT and apply!

Excited to share our new work in Molecular Neurodegeneration, showing that α-synuclein co-pathology is common in Alzheimer’s and accelerates amyloid-related tau accumulation, supporting its role as a tau co-aggregation factor. doi.org/10.1186/s13024…

'Alpha #synuclein co-pathology is associated with accelerated #amyloid-driven tau accumulation in #AlzheimersDisease' Nicolai Franzmeier Nico Franzmeier Sebastian Roemer-Cassiano Alexander Maximilian Bernhardt...Johannes Levin MatthiasBrendel Günter U. Höglinger Universität München bit.ly/4bCVh0H

Our team in London is hiring! If you want to come work with a wonderful group of researchers on investigating the frontiers of autonomous open-ended agents that help humans be better at doing things we love, come have a look. Link in post below 👇

نوروز مبارک با آرزوی سالی سرشار از آزادی، شادی،‌و سلامتی برای همه

Highly recommended PhD opportunity! Great supervisor, great datasets, very innovative methods and tools to understand the complex mechanisms of AD. Downside: you need to be really smart to understand all their work ;)

Jafar Panahi is only the fourth director—after Henri-Georges Clouzot, Michelangelo Antonioni, and Robert Altman—to win the big three film festival prizes: the Cannes Palme d'or, the Berlin Golden Bear, and the Venice Golden Lion, and the first Camera d'or winner to win the Palme.

How does the brain reorganize in the context of age and AD? Are functional changes in age and AD similar? Are these changes dynamic across the age/AD spectrum? We unpack these questions in a sample of N=973 with AD biomarkers Preprint: tinyurl.com/ymv8s7h8 1/ ⬇️🧵

Happy to share new work by Carla Palleis in MDS, showing that brain networks route neurodegeneration patterns in PSP => This suggests that grey matter atrophy expands across connected brain regions, potentially following tau accumulation in PSP doi.org/10.1002/mds.30…

Very happy to share our 2nd paper today, led by Lukas Frontzkowski: We developed a novel data driven reference region for PI-2620 PET tailored to assess 4R tauopathies, improving i) PSP vs. control separation and ii) PET associations with clinical scores doi.org/10.1007/s00259…

I just requested, on behalf of The Left in the European Parliament, that the European Parliament condemn the illegal Israeli attack on Iran. But the mainstream political parties refused. When Russia illegally attacks Ukraine, they condemn it. When Israel illegally attacks Iran, they refuse to do the same

Ted Cruz on Iran. Full interview tomorrow.

CNN put together a collection of clips of Netanyahu warning Iran is close to a nuclear weapon going back to 1996

Both the US and Israel are determined to prevent Iran from developing nuclear weapons, despite being nuclear powers themselves. While Israel has never officially confirmed that it possesses nuclear weapons, there is substantial evidence to suggest that it does.