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A study on #morphogenetic constrains in the development of #gastruloids and its implications for mouse gastrulation biorxiv.org/content/10.110…… Effect of initial size on gene expression, polarization & elongation @AMA_Lab led by Ulla Fiuza #IInNumbersWeTrust #NotInTheGenes

🚨New preprint alert! Excited to share the latest work from our lab. In this study Ulla, Sara and colleagues investigated the role of size in #gastruloid AP patterning, tissue mechanics and elongation, with potential implications for mouse development! biorxiv.org/content/10.110…

If you have pre-registered for the 2025 Gastruloid Meeting, you will soon receive an e-mail asking you to finalize your registration (deadline 12th Jan 2025). We are expecting almost 100 attendees and will have the pleasure to have Dr Naomi Moris and David Turner as invited speakers!

For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here biorxiv.org/content/10.110… led by André Dias we uncover the reason

Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan. biorxiv.org/content/10.110…

🚨 New preprint alert! In the latest work from our lab, André Dias and colleagues dissected the role of a Wnt/Nodal antagonistic signalling module in patterning the emerging mammalian body plan, using #gastruloids as a model. Cool work!

1/2 Early development requires fit cells. Following @MTorrescnic & T. Rodriguez, led by Joshua Frenster we've developed a #gastruloid model #CellCompetition biorxiv.org/content/10.110… that recapitulate cell competition as in the embryo & open up experimental possibilities

🚨 A new preprint from our lab is out now! In this study, Joshua Frenster and colleagues show that #gastruloids are a powerful and versatile tool to study the cellular and molecular bases of mammalian cell competition at the time of gastrulation. Nice work! biorxiv.org/content/10.110…

Amidst these troubling times, I have some positive personal news to share: I will be joining IMBA imbavienna.bsky.social as a new group leader this fall! 🎉 I am excited for fun projects, surprising discoveries, and great discussions within the fantastic science community Vienna BioCenter.

Today we kicked off the first day of the 2025 Gastruloid Meeting in Barcelona with a talk by our invited speaker David Turner. Thanks to all the presenters and almost 100 attendees for great discussions! Looking forward to what comes tomorrow 🙌

More fascinating talks today at the 2025 Gastruloid Meeting!

The 2025 Gastruloid Meeting in Barcelona has already come to an end, with fascinating closing remarks by Dr Naomi Moris. Many thanks to all of you for joining us and sharing your research, it was a wonderful gathering!

Being able to bring together part of the #gastruloid community in this special meeting was incredible. Thank you all for participating in this event, and keep up the great science!

Perhaps the beginning of something. #Gastruloid community, Barcelona 2025 after Marseille 2024 Nice to see human self organization at work in these challenging times. It was good to see US colleagues joining us and breathing european air! We appreciated their joining in.

We’re looking for PhD students to join the lab! 🧫🧑‍🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/ ‼️Deadline: April 15‼️

Just published a new edition of “Principles of Development’ from “Wolpert’s Principles of Development’ to honour his memory and the origin of this textbooks that aims at distilling the, sometimes elusive, principles underlying animal and plant development shorturl.at/LrOxn

We've just updated our manuscript to a more 'publishable' version! biorxiv.org/content/10.110… New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates

The newest version of our recent preprint is out now!