Checkpoint inhibitor induced colitis nicely reviewed by Loris Lopetuso at 5 Nations IBD meeting

Today on #WorldIBDDay, we stand with the 10M+ people living with Crohn’s & colitis. At Altis, we support IBD research with #RepliGut, our human intestinal model advancing studies in inflammation, repair & barrier function. 💜 #AltisBiosystems #IBDhasnoborders #worldibdday2025

Just launched: RepliGut Immune Co-Culture Human colon epithelium + THP-1 macrophages ➤ Models innate immune inflammation ➤ Responds to tofacitinib + adalimumab ➤ TEER, viability, cytokines For gut barrier + IBD studies → hubs.ly/Q03nh2600

Over half a million people in the UK live with Crohn's or Colitis. They're invisible, lifelong conditions with devastating impact, and no known cure. Let's make the invisible, visible. Get involved: crohnsandcolitis.org.uk/get-involved/w… #WorldIBDDay #CourageLooksLikeThis

New online! The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection bit.ly/4k3ZD49

Caco-2 doesn’t do inflammation. Organoids lack access + reproducibility. We built something in between. 🧬 Human gut epithelium 🧫 + THP-1 macrophages 🔥 LPS/IFN-γ triggers barrier breakdown 💊 Drugs mitigate response RepliGut® Co-Culture is here → hubs.ly/Q03nKsZZ0

As we honor those who served and sacrificed this #MemorialDay, we’re reminded of our responsibility to protect life and health. At Altis, that means advancing human-relevant models like RepliGut® to help develop safer, more effective therapies. 🇺🇸🧬

Customers wanted: 🔹 Human-relevant inflammation model 🔹 Easy to run 🔹 Scalable readouts We delivered. RepliGut® Immune Co-Culture = epithelium + macrophages in 96-well format Works w/ tofacitinib & adalimumab. Details → hubs.ly/Q03pjBgN0

"The Microbiome for Clinicians" a new, open-access review of progress, limitations, and next steps Cell cell.com/cell/fulltext/…

REVIEW | M van Hul, P Cani et al. (UC Louvain): This Review discusses the impact of the gut #microbiota on #cancer and on cancer #therapy 🦠💊 FREE to read: nature.com/articles/s4225…

Mediterranean-style diets: good for the microbiome, good for the gut

Heading to MPS World Summit in Brussels? Stop by Booth #427 to explore RepliGut® Systems + our new Co-culture platform—ideal for modeling gut-immune inflammation and cytokine response. 🗓️ June 10–14 | Tour & Taxi #MPS2025 #RepliGut #IBD #RepliGut #RepliGutCoCulture #IBDResearch

What if metabolites produced by a Mediterranean diet contribute to its benefits in #ulcerativecolitis❓ Natasha Haskey PhD RD 👩‍🔬🔬🍉 & colleagues found that following a Med diet is associated with specific metabolite changes linked to ⬇ inflammation in UC: ✅ ⬇ fecal sphingolipids 💡 These

Researchers have identified 3 types of nerve cells connected to the intestinal villi, which could lead to a better understanding of #IBD and other diseases. tinyurl.com/gutnerve #crohns

🎯Catch Altis CEO Dr. Ben Scruggss at #MPS2025! Poster #295: RepliGut® Crypt 📅 June 11 @ 4:30 PM Talk: In vitro model for DMPK prediction 📅 June 12 @ 12:40 PM 🎤 Track 3, Session 3.4 Learn how human intestinal systems are reshaping drug discovery. #MPS2025 #RepliGut #DMPK

We’re on our way to Brussels! RepliGut® Co-culture is launching at #MPS2025—stop by Booth #427 to learn how it models inflammation & barrier damage in vitro. #RepliGutCoCulture #IBD

There's still time to submit for this year's NASPGHAN foundation grants for 2025! 💸With grants available at all career levels and interests, spanning from Carbohydrate malabsorption to Liver disease!!! Grant submissions due on 7/1!! tinyurl.com/jcu2shwk

🎙️The next generation of human gut models is here. Learn how RepliGut® redefines PK and GI tox prediction—beyond Caco-2. 📅 Register now: hubs.ly/Q03rC9yM0 🔬 For scientists in DMPK & tox #DrugDiscovery #RepliGut #Webinar #DMPK #toxchat

🎤 Altis is on stage today at #MPS2025! 🧪 Jarrett Bliton presents Poster #280 10:00–11:30 | Session 3 🧬 CEO Ben Scruggs speaks at Track 3 12:40–1:00 PM | DMPK Session Catch both talks—and visit us at Booth #427! #RepliGutCoCulture #DrugDiscovery #IBD

Animal models miss key human immune responses in IBD. This gut-immune co-culture system—built on primary human cells—brings relevance, reproducibility, and throughput to drug screening. Built for IBD. Learn more → hubs.ly/Q03s9YVp0