In drug development, macrocyclic peptides aren’t too big or too small. They’re just right to target difficult protein-protein interactions happening within cells. “You completely have the best of both worlds,” Douglas Johns Merck told Allison Whitten, PhD. ow.ly/RIbP50RyA4t

Young blood reverses aging in old organs. Article by Allison Whitten in Drug Discovery News. drugdiscoverynews.com/young-blood-re…

I had so much fun making this podcast episode and would love if you gave it a listen! Also, check out our episode page for some photos I took at the UC Irvine nuclear reactor lab! ⚛️ drugdiscoverynews.com/from-warhead-t…

Researchers are exploring young blood as a treatment to rejuvenate aging organs. “In a way, it’s nature’s cocktail or nature’s elixir,” Tony Wyss-Coray of Stanford University told Allison Whitten, PhD. ow.ly/pqOO50RPOJR

What if Alzheimer’s disease (AD) takes root in the brain long before symptoms arise? Jenny Hsieh of UT San Antonio studied brain organoids with a mutation related to early-onset AD and found abnormalities in development. Allison Whitten, PhD reports. drugdiscoverynews.com/tracing-alzhei…

“Prioritizing creativity can itself lead to tangible advances. Many of the most famous scientific discoveries never would have happened without it,” wrote Allison Whitten, PhD in a new editorial on the need for creativity in science. Read it here: ow.ly/T83450RyB5B

🤯 Key brain signal linked to memory formation deteriorates after sleep deprivation, finds a study in rats. Even a night of normal slumber after a poor night’s sleep isn’t enough to fix the brain signal. For nature, w/ Kamran Diba کامران دیبا Ted Abel nature.com/articles/d4158…

Researchers led by eric hoyeon song Yale School of Medicine uncovered a never before seen immunological connection between the eye and brain that confers shared immunity to pathogens. Allison Whitten, PhD reports on the new findings. Learn more about our Image of the Month: ow.ly/nbFJ50SLlH0

In the 1990s, Pfizer Inc. shelved an effective antipsychotic drug due to its side effects. Years later, Andrew Miller, now advisor to Bristol Myers Squibb, found a way to minimize the side effects. The new drug could become the first in a new class of antipsychotics. ow.ly/zG5n50SQu9L

Heart muscle can’t regrow after a heart attack. But researchers like Hesham Sadek, Jens Tank, Charles Murry, and Jim Martin are getting closer than ever before. Hear about the latest progress in this new DDN Dialogues podcast with Allison Whitten, PhD: ow.ly/U7wW50SXPii

After more than 70 years, a new antipsychotic drug is on the horizon. “The idea that [KarXT] is going to be the first ever non-dopamine based treatment—hopefully—it's amazing to think about,” Andrew Miller Bristol Myers Squibb told Allison Whitten, PhD. Read more: ow.ly/NhJh50SQubS

What if doctors could treat heart attacks with a strong dose of regeneration? In this new DDN Dialogues podcast, Allison Whitten, PhD spoke with experts who are not too far off from turning that into a reality. 🎧Listen here: ow.ly/qt5550SXPnk

Opioid overdose can be treated with naloxone. But for stimulant drug overdoses, there are no treatments. Allison Whitten, PhD spoke with researchers who are attempting to change that. ow.ly/y8v150TeLik

Researchers are trying out some pretty unexpected ways to get the heart to regenerate after a heart attack. Jens Tank DLR - English told Allison Whitten, PhD about his team’s work putting patients into the largest hypoxic chamber in the world. 🎧 Listen here: ow.ly/OVf650SXPqU

Today, the FDA approved the first new type of drug for schizophrenia in 70 years. Check out Allison Whitten, PhD's deep dive into the story behind this new drug for Drug Discovery News: drugdiscoverynews.com/after-70-years…

What if we could prevent autoimmune diseases from ever starting? Allison Whitten, PhD interviewed researchers working to make that happen, including John E. Harris, MD, PhD, Judith James, Kevin Deane, Aaron Michels, Kevan Herold, and Francisco Quintana. Read more: ow.ly/prxb50TneSf

“It’s particularly frustrating that, despite the fact that we've learned so much about addiction, it has been very difficult to translate that into new treatments,” Eric J. Nestler, MD, PhD told Allison Whitten, PhD. Read more about drug discovery efforts for addiction: ow.ly/4FgM50TeLof

Skin cancer may be preventable in the future with a new gel developed by Kenneth Y. Tsai, Kavita sarin, and NFlection Therapeutics. Allison Whitten, PhD interviewed Kenneth Y. Tsai to find out more. ow.ly/HIb750Ts0Cu

Gene therapies for Alzheimer’s disease are under study in clinical trials. They could one day heal the brain of patients or help prevent Alzheimer’s disease from ever starting. Read more in this story by Allison Whitten, PhD: ow.ly/Q4UQ50UsaTu

Allison Whitten Allison Whitten, PhD updates concepts informing the safety of GLP-1 medicines for Drug Discovery News drugdiscoverynews.com/illuminating-t…