We have an exciting opportunity for a postdoctoral fellowship in Structural Biology and biochemical / biophysical characterization of protein complexes in the Wnt signaling cascade. Come join our teams and perform impactful research! tinyurl.com/GNESBPD

Congratulations to our own Ardan Patwardhan for receiving the Scientific Achievement Award from the RMS for his essential work in progressing the archiving and sharing of EM data, including the #EMDB_EMPIAR archives. #SharingIsCaring #OpenScienceAcceleratesResearch

This toy example may change how you look at tSNE & UMAP. They find clusters in the most uniform data possible.

Disease-specific tau filaments assemble via polymorphic intermediates. This is what had me so excited for the past few weeks! The amazing Sofia Lövestam has solved another 163 #cryoEM structures! 🥳🥳🥳A #tweetorial below. As always, with Michel Goedert. biorxiv.org/cgi/content/sh…

I could stare at that pipe work for hours.

When you literally took hip hop around the world and had to explain what it is. 👑🕺🏿🔥 🇨🇱 🇪🇹 🇳🇬 🇿🇦 🇧🇷 🇲🇽 🇮🇹 🇯🇵 🇬🇧 🇵🇭 🇷🇴 🇩🇪 🇩🇰 🇮🇪 🇫🇷 🇰🇷 🏴󠁧󠁢󠁥󠁮󠁧󠁿 🇵🇷 🇩🇴 🇯🇲 🇹🇹

Don’t miss our LMB Through the Years interview with Nigel Unwin, who covers the unusual uses for spider silk, his first encounter with the torpedo ray acetylcholine receptor, and the foundation of the LMB’s Neurobiology Division. Full interview: www3.mrc-lmb.cam.ac.uk/sites/lmbthrou… #LMBat60

I've been playing a bit more with ChimeraX lately - it is fantastic and beautiful software, and built by an extremely helpful and patient team of developers! Here are some settings and aliases/shortcuts that I find handy: github.com/olibclarke/chi…

My indispensable right hand Natalya Dudkina is hiring, join our exciting R&D group at Thermo Fisher Scientific as Application Engineer, Cryo-EM. RT please! jobs.thermofisher.com/GmABVUk

Refining my first ever (!!!) x-ray crystal structure in #ISOLDE. Tristan Croll - am I correct that symmetry mates are ignored by the simulations? I can see water networks at crystal interfaces and wish the waters could "feel" each other...

I am @alexisrohou.bsky.social. Community seems to be building up over there in a way that it hasn't really done over at Mastodon. Come join us! I have a couple of invite codes.

I have a few more invite codes - DM me and come over to the blue expanse

I have a couple more invite codes to the sky. Anyone? Tristan Croll maybe? Oli B. Clarke ?

Bluesky is now open - no need for an invite. bsky.social/about/blog/02-…

Wanna do KRAS (20kDa) with a small molecule ligand and you have a Fab? Oh and sub 3 biorxiv.org/content/10.110…

Thrilled to share a pre-print describing an elegant solution to overcome target size limitation of single particle #cryoEM, where we demonstrate high resolution (2.3 – 2.5 Å) structure determination of small (~20 kDa) ordered proteins using cryoEM! biorxiv.org/content/10.110…

It is of paramount importance that the management of a research lab be composed of reputable scientists. Their main jobs are to: 1. Identify, recruit, and retain brilliant and creative people. 2. Give them the environment, resources, and freedom to do their best work. 3.