Beyond grateful to share two co-first author papers that came out in nature!! With Amit Vinograd, we provide causal evidence for a line attractor in the mammalian brain! And with Mengyu Liu 刘孟宇, we show that line attractors might be a common mechanism for emotions beyond anger!

If you’re attending #sfn2024 #SfN24 and would like to chat about our recent publication about #orexin and exercise/eating decisions, visit me Monday morning at PSTR185.06!

My paper is out!! 🎉 "Opponent control of reinforcement by striatal dopamine and serotonin", nature Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠 THREAD ⬇️ 1/n

Reviewed preprint is online in @elife: Reviewers raised some important points, revisions coming soon! Orexin population activity precisely reflects net body movement across behavioral and metabolic states doi.org/10.7554/eLife.…

Our new paper is out in Cell Reports We show an inhibitory response of Orexin receptor type 2 (Ox2R) in a subset of MCH neurons. doi.org/10.1016/j.celr…

Newest paper is on BioRxiv! We examine hypothalamic orexin (and MCH!) -producing neurons for their role in regulating decision policy complexity. Huge thanks to my supervisors Denis Burdakov and Rafael Polania biorxiv.org/content/10.110…

The first step of any meaningful pursuit is to severely underestimate its difficulty.

Hunger-driving AgRP neurons are REM-active, and similarly re-activate during cataplexy. Hot off the press from the Burdakov lab! biorxiv.org/content/10.110…

Absolutely an honor to meet your lab! Great stuff happening in Beijing, thanks for hosting me😊!

Super excited to share my PhD work, out now in nature. Here, my fantastic coauthors and I delved into whether mice could form memories of temperature experiences. 🐭💭❄️ Check out our tweetorial 🧵below: Full paper at: nature.com/articles/s4158…

The future of science is Chinese. It’s not just the USA who is falling behind; we feel it here in Europe as well. Politics, budget cuts, and a general glorification of ignorance are poisoning the whole of western science.

Be skeptical of any analysis in which the least powerful people are the most responsible for your problems

In our Learning Club CMC lab tomorrow (= July 3rd, Thursday, 2 PM CET), Alexander Lee Tesmer will tell us about his recent paper (biorxiv.org/content/10.110…). If you'd like to attend, send an empty email to [email protected] to get the link! Thanks Alex!

Just released today in Nature Communications. “Body temperature regulates glucose metabolism and torpid behavior” Using a hibernation-like mouse model (QIH), we uncovered key links between thermoregulation and glucose metabolism. doi.org/10.1038/s41467…

(1/3) Excited to introduce our new GRAB sensors for a series of steroid hormones! These tools enable real-time detection of steroid hormone dynamics in vivo🐭🧠.Happy to share these sensors and welcome any feedback!Please contact [email protected] for information.

How do animals decide if they should forage for food or stay home to take care of newborn offspring? Whose needs come first? For my PhD work now out in nature, we examined how hunger and parenting neurons interact and are reshaped postpartum in mice 🧵⬇️ nature.com/articles/s4158…

In mice, orexin neurons multiplex the encoding of rapid body-movements with slow changes in blood glucose. The extent to which these neurons correlate with movement across behavioral and metabolic states surprised us! Now a Version of Record in eLife - the journal. doi.org/10.7554/eLife.…

A hypothalamic circuit for anticipating future changes in energy balance. biorxiv.org/content/10.110… #biorxiv_neursci

Online now: Hunger modulates exploration through suppression of dopamine signaling in the tail of the striatum dlvr.it/TNRPCh