The final (formatted) version of our nature study on bat virus spillover is now online nature.com/articles/s4158… Over the 25 year study, we observed a transition from large nomadic bat populations feeding in native forests to small resident populations feeding in human-areas.

Some mvRNAs, such as PA60 and PA66 (or PB1-64 and PB1-66), accumulate early - between 3 & 6 hours post infection (hpi). More highly produced mvRNAs tend to accumulate at earlier times, to boot. (10/X)

We also looked at mvRNA subcellular localization using biochemical fractionation, and found that PA-60 and PA-66 accumulate in the cytoplasm between 6 hpi and 8 hpi. Also, PA-60 is found more frequently in the nucleus than PA-66. (12/X)

We are also grateful for funding from NIH, CDC, the Bill and Melinda Gates Foundation, the Wellcome Trust, and the Center for Health and Wellbeing at Princeton. (18/X)

Secret Santa and goodbye party for Emmanuelle Pitré with the lab!

Congratulations to @charrigb on passing her Cambridge PhD viva! Many thanks to Ian Brierley and Elly.Gaunt_lab 💙 for examining (and Elly for taking the chaotic train journey)!

Deep sadness over 𝙱𝚛𝚎𝚝𝚝 𝙻𝚒𝚗𝚍𝚎𝚗𝚋𝚊𝚌𝚑 🌊’s passing 💔 His love of virology was truly inspiring. Please consider supporting Brett’s legacy by contributing to the Brett Lindenbach Virology Fund, to help train the next generation of scientists in virology. medicine.yale.edu/news-article/t…

Transient RNA structures contribute to highly pathogenic flu emergence! Fantastic work by Mathis Funk and Mathilde Richard now on BioRxiv: biorxiv.org/content/10.110… For supporting data see: science.org/doi/10.1126/sc…

Elucidation of the molecular mechanism by which avian influenza virus rapidly increases its ability to cause mortality. #vogelgriep

Congratulations Emmanuelle Pitré on passing her PhD viva! Thanks to examiners Steve Goodbourn and Julia Kenyon Cambridge Pathology!

How do viruses go from LPAI to HPAI? The RNA structure use to trap polymerase drives insertions into the cleavage site. Insertion frequencies strongly affected by substitutions in flanking regions. Big implications of this study!!! 👉biorxiv.org/content/10.110…

🔬Exciting Opportunity! 🌐Join us at @kavlioxford in a mission to unravel gene expression inside the jungle of live cells! Intrigued by single molecules, RNA, condensates, AI and bacteria? Read on! 🚀Two 4-year positions. RT pls! #ScienceJobs #Postdoc #bacteria #singlemolecule🌟

A very alarming but not unexpected development. The potential consequences on a local and global scale are concerning.

Come join us! Great environment with many exciting projects available! 🤗😃⬇️

Now out in @nature: Artificial Intelligence and Illusions of Understanding in Scientific Research, coauthored with the brilliant Lisa Messeri and edited by the supremely talented Mary Elizabeth Link: nature.com/articles/s4158… Open version: rdcu.be/dAv39 🧵

The NEW Flu Hub website is live! ow.ly/eRcW50QLKT5 What is the #FluHub website? It centralizes NIAID research that contributes to the Universal Influenza Vaccine Strategic Plan. Find contributing networks, computational resources, cohort studies, reagents, and more!

Congratulations Princeton MolBio PhD student Kaleigh Remick for being awarded an U.S. National Science Foundation GRFP for her influenza virus replication project!

This west coast IPA is joining brangwynnelab and AJ te Velthuis in about a week! Thank you Erica OllmannSaphire and the lab for everything🦋.