What does AlphaFold3 learn about antigen and nanobody docking, and what remains unsolved? The article investigates the performance of AlphaFold3 (AF3) in the context of antibody and nanobody docking with antigens, focusing on its successes and areas requiring further

The first complete 3D reconstruction and morphofunctional mapping of an insect eye. elifesciences.org/reviewed-prepr…

Ribosomes: the one thing we all have in common from bacteria to humans. Learn more at smart-biology.com #biology #3D #science #EdTech

The human brain contains an entire spoon’s worth of microplastics - levels were even higher in those with dementia. 🧵1/10

New preprint on #TDA: "Modeling Misfolded Protein Spread in #Alzheimer 's via Higher-Order Contagion" by Wardynsky, Iacopo Iacopini, Giovanni Petri & Latora. We show how high-order #graphs improve predictions of misfolded protein spreading vs. SOTA models. 🔗 medrxiv.org/content/10.110…

Energy, momentum, pressure, stress, etc. are all just different ways of quantifying the same basic thing: how our perceptions of space and time get distorted over time. And once you internalize this, it allows you to think about these concepts in a much more general way. (1/12)

Most code in biology will run on GPUs over the next decade. Bioinformatics workflows, protein engineering models, virtual cells. Excited to partner with NVIDIA NVIDIA Healthcare to write new tools + consolidate access to existing models / hardware to biotechs across the industry

It is with great pleasure I announce to you the book with all the papers presented at the latest MICCAI meets #Africa "Medical Information Computing"🪘 🛖🦁🥥🌴🌳is online: link.springer.com/book/10.1007/9… a big thank to Celia Cintas IBM Research CAMERA MRI AFRICA MAILAB Ugumba Kwikima #AI

Does ADHD and OCD stem from the same neural circuitry? Despite their opposing clinical features, ADHD and OCD share frontostriatal circuit dysfunction, suggesting a neurobiological overlap rather than entirely distinct conditions. (Cabarkapa et al., 2019) Let’s dive in. 🧵⬇️

My PhD work is now out! Here, we set out to formalize the neural manifold hypothesis and explain several experimental phenomena in systems neuroscience with a single theoretical framework. I highly recommend giving it a read, though tweetprint come much later!

We have a new paper on #Neuroimage clinical.Editorial team - Neuroimage Clinical:🧠 #Stroke reshapes #brain function beyond the lesion site. We map functional connectivity gradients fixing hemodynamic lag, revealing predictable shifts tied to behavior sciencedirect.com/science/articl… #Neuroscience #StrokeRecovery

This week, I had the privilege of teaching two modules on Computational Structural Biology, focusing on Molecular Docking and Dynamics, as part of an Applied Bioinformatics course. It was an enriching experience to exchange ideas and insights with so many brilliant minds!

🚀 Just released the official GitHub repo for our paper, "Intelligence at the Edge of Chaos"! We explore how complexity shapes intelligence in large language models trained on cellular automata. Paper: arxiv.org/abs/2410.02536 Repo: github.com/vandijklab/Int…

Advancing stroke imaging analysis with interpretable AI and effective connectivity models medicalxpress.com/news/2025-02-a…

We introduce EvoFlow-RNA, a masked diffusion model with the ability to unconditionally generate (and optimize) novel, naturalistic non-coding RNAs. We show s.o.t.a. results on RNA representation learning, unconditional RNA design, and more! 💡 🧵 (1/11)

Today marks the beginning of OpenRxiv, which replaces bioRxiv and medRxiv, the world's largest preprint platform for life and medical science openrxiv

BrainGPT is can generate #radiology reports directly from 3D #brain CT scans! It is 𝘁𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹𝗹𝘆 𝘃𝗶𝘀𝘂𝗮𝗹 𝗶𝗻𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝗼𝗻-𝘁𝘂𝗻𝗲𝗱 #𝗔𝗜 𝗺𝗼𝗱𝗲𝗹 𝗳𝗼𝗿 𝗯𝗿𝗮𝗶𝗻 𝗖𝗧 𝗿𝗲𝗽𝗼𝗿𝘁 𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻 nature.com/articles/s4146… #LLM #vision

Our work on old school #machinelearning 🤖for separating time series data including #Spike trains from MEA with mice #brain 🧠 is out: "Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets" sciencedirect.com/science/articl…

Nature Neuroscience Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks nature.com/articles/s4159…

New paper out on @iscienc: "From Knowledge Generation to Knowledge Verification: Examining the BioMedical Generative Capabilities of #ChatGPT" By .Dr. Ahmed Abdeen Hamed, Ph.D. and Co. About checking with other sources whether #llms lie cell.com/iscience/fullt…