Andrew P. Han
@ahangw
Staff reporter, @GenomeWeb. Covering genome editing and engineering. CRISPR/Cas9, TALENs, ZFNs, SynBio. Tweets/opinions my own. RTs not endorsements.
ID: 3097238530
http://genomeweb.com 19-03-2015 17:03:53
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Wednesday (3/17), 5 p.m. ET: At the one-year mark of the pandemic, join The Atlantic science writers @yayitsrob, Ed Yong is not here and Sarah Zhang, as well as senior editor Sarah Laskow, for a discussion of the "pandemic beat." Register: bit.ly/2Q3189L
Michael 英泉 Eisen ANGPTL3 was first connected to LDL cholesterol levels by GWAS, ultimately leading to an approved treatment for homozygous familial hypercholesterolemia (evinacumab) and other treatments in development.
Michael 英泉 Eisen nextgenseek TYK2 is the sitter. Not sure if you count PCSK9 or not. Both rare and common disease highly predictive (odds ratio) for success in phase II (right disease trial) and in many pharma now working into assessment for Phase II trials (have you chosen the right disease) >>
First draft is ready on Arxiv. Many thanks to Martijn van den Ende Sylvain Barbot and Dr. Susan Hough and others. I will try to submit it soon. arxiv.org/abs/2303.11802