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High-throughput magnetic separator for purifying IgG from 500 clinical samples/day. Printable design: a360.co/43naWNT

The Dean of the Medical Faculty confers the Götz Prize to Jiang-An Yin, senior scientist of the Aguzzi lab, for his work on expanding the reach of CRISPR screens 👏👏👏

Dear applicants, if you ask ChatGPT to write your application, at least prompt it to obfuscate these obvious tell-tale signs. In real life, NOBODY praises my work so effusively 😆😆😆

I was an early adopter of speech-to-text technologies. 20 yrs ago I dictated into the software a prion review citing my distinguished colleagues Stan Prusiner and Jiří Safar. It wrote down "Prisoners suffer". 😆 cell.com/cell/fulltext/…

How do you represent 3-dimensional datapoints on 2d screens? 3d scatterplot are horrible, yet massive dimensionality reduction kills all nuances. Maybe one could make "wiggling GIFs" to help identify the position of datapoints in space?

Mountain-biking up Mt. Kamor with dermatologist extraordinaire Lukas Villiger. He publishes Nature papers like hot bagels (latest one: nature.com/articles/s4158…) but I climb faster!

Two papers, three dimensions! Anna Maria Reuss describes a generic technique for 3D-histology of human archival paraffin blocks, and Francesca Catto shows breathtaking videos of mouse brains with Alzheimer's. journals.plos.org/plosone/articl… biorxiv.org/content/10.110…

These magnetic beads were found in the lab of Plinius the Elder in Pompei perfectly preserved by the eruption of Mt. Vesuvius in 79 AD.

At some point in life, being still able to do this twice daily, before dawn + at sunset, without any e-motor, come hell or high water, becomes more important than getting the next ERC grant.

There is no such thing as bad weather. Only inappropriate attire.

I may be paranoid, but for CRISPR-transactivation screens I always check the chromosomal location of the hits. The VPR transactivator is dynamite; if multiple hits are just few kilobases apart (PRNP vs PRND), they may be spuriously coactivated false-positives.

The vilification of international students is a depressing, ignorant and callous development. Most of them have backgrounds that wouldn't be considered "privileged" by US standards. I was one myself, and I've trained dozens of them.

Isn't it amazing that (1) high-affinity α-tau antibodies exist in 5% of everybody, (2) they increase with age and (3) correlate with a nephrometabolic syndrome which to my knowledge was never described before. Bad news for α-τ immunotherapy methinks. medrxiv.org/content/10.110…