Latest preprint from our lab: a myosin VI-Dock7 axis controls RAC1 in follower cells to promote collective motion!! Great collaboration with Scita_Lab ً and Fabio Giavazzi Istituto Confucio di Milano biorxiv.org/cgi/content/sh…

Online today! 👉Mutated #AxonGuidance gene #PLXNB2 sustains growth and invasiveness of stem cells isolated from #CancerOfUnknownPrimary By Enrico Giraudo, L. Tamagnone & colleagues Istituto di Candiolo - FPO IRCCS Università di Torino Università Cattolica 🗞️Read #openaccess: doi.org/10.15252/emmm.…

Our paper is now out!! Great and exciting collaborative work. Thank you all. x.com/EmboMolMed/sta…

Interested in a Post-doc Ivaska Lab TurkuBioscience working on novel anti-invasive barriers in BrCa - cutting edge cell biology/imaging/HTS/clinical collaboration? Watch this space! We will be shortly opening a call a post-doc Worldwide Cancer Research granted 3 year funding

We are glad to host "In search of normality: looking for molecular strategies to repair #cancer blood vessels" a seminar by Guido Serini 🗓️ July, 20th at 2.30pm 🏛️ Room A104, Povo 1 ℹ️ webmagazine.unitn.it/node/117297/ #blood #bloodtumor

Looking very much forward to my visit to CIBIO - UniTrento of Thu July 20th, meeting and discussing with its scientists

Thrilled to see our latest work “Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function” led by Alice Santi and Emily Kay on the cover of Science Signaling. Beautiful images by BAIR_Beatson Paper here 👇🏻 science.org/doi/10.1126/sc…

Our latest paper! A promising avenue for therapeutic intervention in fibroses, characterized by excessive ECM production, via targeted inhibition of TANGO1-mediated ER export. TANGO1 inhibitors reduce collagen secretion and limit tissue scarring nature.com/articles/s4146…

Thrilled to announce our latest research just published in Nature Communications! We investigated how therapy induces therapy resistance via cell state transition and vessel co-option in glioblastoma. (1/11) nature.com/articles/s4146… #GBM #btsm #Research

💥Check out our latest work just out Nature Communications 🔬#Platelets shape the outgrowth of #metastasis, even growing & established foci. 🎯We further identified #targets and tools with therapeutic potential rdcu.be/dHL7i #mouse #zebrafish #imaging #Immunology #hemostasis

Check out our latest review in which we discuss the recent exciting discoveries on single-cell and collective ERK signaling dynamics!

Rab7 deficiency induces lysosome formation from recycling endosomes leading to an increased degradation of cell surface proteins biorxiv.org/content/10.110…

Very pleased to share our latest preprint on MAPK dynamics and cell fate decisions in lung cancer biorxiv.org/content/10.110… . Does EGFR mutation mean MAPK is always on? NO, it shows dramatic pulses👇1/4

Now online! Ligand binding initiates single-molecule integrin conformational activation dlvr.it/T791P4

We just updated our preprint, "The structure of an Amyloid Precursor Protein/talin complex indicates a mechanical basis of Alzheimer's Disease" to include beautiful new proximity ligation data of talin and APP in neurons. 😍 @jcl_lambert Inst of Systems, Molecular & Integrative Biology biorxiv.org/content/10.110…

September issue of Journal of Cell Biology also contains our new paper on TLNRD1 (talin rod domain containing 1) protein and its role in the Cerebral Cavernous Malformation complex. rupress.org/jcb/article/22… @guijacquemet Inst of Systems, Molecular & Integrative Biology School of Biosciences, University of Kent Turun yliopisto - University of Turku

Our paper is now out!! Great and exciting collaborative work. Thank you all. PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination aacrjournals.org/cancerimmunolr…

Local weakening of cell-extracellular matrix adhesion triggers basal epithelial tissue folding Andrea Valencia-Expósito, María Martín-Bermudo et al embopress.org/doi/full/10.10…

Mechanobiological mechanism of cyclic stretch-induced cell columnarization dlvr.it/TKdwss