Cells or Galaxies? You know I don't take pictures of galaxies...... #CellBiology

When it's not your day🧐

A cell videoed through a microscope. The powerhouses/overlords of the cell, mitochondria, are shown in yellow. The nucleus is shown in cyan and actin filaments are shown in magenta. #CellBiology

Cells from a cow photographed through a microscope. DNA in the nuclei (red), the powerhouses/overlords of the cell, mitochondria (yellow), and actin filaments (blue) are shown. #CellBiology

Molecular dynamics simulations in mixed reality! With Luciano Abriata and Lucien Krapp we’re scaling our multi-user WebXR platform to enable immersive molecular simulations, fully based on web technologies. Stay tuned, lots of cool stuff coming soon! Three.js #WebXR #Quest3

🪰By infusing a virtual fruit fly with #AI, Janelia & Google DeepMind scientists created a computerized insect that can walk & fly just like the real thing➡️ hhmi.news/3Rwop0w 🤖Read more about this work, first published in a #preprint in 2024➡️ hhmi.news/4cGAVUW

mScarlet3-H (aka mYongHong) makes a great pair with mBaoJin (nature.com/articles/s4159…) for long-term live cell imaging. All plasmids can be requested for free from WeKwikGene wekwikgene.wllsb.edu.cn

Fluorescent labeling of proteins in vitro and in vivo using encoded peptide tags sciencedirect.com/science/articl…

David Stern and Igor Siwanowicz HHMI | Janelia created this image which shows a female aphid nymph that just started inducing the formation of a gall in the tissues of a budding witch hazel leaf. These images highlight the difference between normal, healthy leaf tissue and the

As a member of numerous editorial boards and a reviewer for 10+ journals, I have come to appreciate grammatical errors and spelling errors. At least I know it was written by a human.

Human mitochondria connect with each other at a distance through thin membrane protrusions called "nanotunnels" As if they are "reaching out for help". Mitochondria in people with mitochondrial diseases show more nanotunnels in healthy mitochondria do. Below is one of the most

MOSAIC large field of view 3D single molecule localization microscopy of mitochondrial outer membranes and nuclear membranes in fixed U2OS cells.

Mitochondrial GSH is essential for metastasis due to it function in signaling and iron homeostasis. We are grateful for the support of The Mark Foundation for Cancer Research and National Cancer Institute for this project. Also thanks to many collaborators Richard Possemato Aslan Tasdogan

MOSAIC lattice light sheet xy projection over 2+ hrs in human retinal pigment epithelial cells of endoplasmic reticulum remodeling (cyan) and transport of vesicles (yellow) containing β4-galactosyltransferase....

We all need mentors, and the further we go in our careers, the more mentors we need. Whether it’s dealing with increasingly complex career situations, considering a career transition, or coping with a career ending, mentors can be an essential source of wisdom and support.

Some unhealthy mitochondria develop onion-like morphology with concentric cristae

❄️Time-deterministic cryo-optical microscopy, developed by researchers at The University of Osaka, Janelia & collaborating institutions, rapidly freezes live cells under an optical microscope, capturing a snapshot of cellular activity in high resolution.

Type 2 Diabetes is in most cases not an irreversible disorder, but a reversible metabolic, energetic state. Below is a solid review evaluating the effectiveness of different nutrition therapies to manage T2D symptoms. The bottomline: by changing diet, lowering carbohydrate/sugar

3D cross-sectional views of the dynamics of chromosomes (H2B, blue) and the endoplasmic reticulum (orange) in interphase and mitotic LLC-PK1 cells over a 50 x 180 um field at 6 sec intervals, as seen in the lattice light sheet structured illumination mode of MOSAIC.

Some mitochondria end up fusing onto themselves, forming "doughnut mitochondria"