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Ever wonder why drug-resistant Mycobacterium tuberculosis is less fit than drug-susceptible Mtb? And how the bacterium can evolve to compensate for that cost?

My second “first author” paper is published by Nucleic Acids Research! We show how one of the proteins I found from the proteomics screen (Enustun et al., Nat Struct Mol Biol, 2023) is important for mRNA transfer from the phage nucleus and for their translation.

The 25th Weintraub Graduate Student Award Symposium has been an amazing day of exceptional talks and fascinating science. These phenomenal scientists truly represent the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub!

I am delighted to share the newest work from the Sternberg Lab, in which we discover RNA-templated gene creation as a mechanism of antiviral immunity. This is a story for anyone who loves molecular biology, and one that repeatedly left us in disbelief. doi.org/10.1101/2024.0…

Our latest research on a highly unexpected mechanism of antiviral immunity by reverse transcriptase-based defense systems is now live on bioRxiv! A remarkable work of science, and art, led by the talented Stephen Tang. Check out his thread to learn more! biorxiv.org/content/10.110…

A versatile bacterial innate immunity protein directly senses two disparate phage proteins biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Congratulations to Dr. Aaron Whiteley, 2024 Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease colorado.edu/lab/aaron-whit… #bwpath

We’re filled with immense pride as we announce our 2024 Boettcher Investigators. Eight leading Colorado biomedical researchers will receive a total of $2 million in grant funds from our Webb-Waring Biomedical Research Program. Read more: boettcherfoundation.org/boettcher-foun…

🚨I'm delighted to announce that I have accepted a position as a tenure-track assistant professor @uiowamed Department of Microbiology and Immunology. We will study the metabolism of Neisseria gonorrhoeae and neutrophils during pathogenesis. Thrilled to see this dream come to fruition!

Very excited to share that Uday @snowkaryote and I will be joining the Microbiology, Immunology, & Cancer Bio Dept UVA-MIC UVA School of Medicine as Assistant Professors this Fall! 🎉 My lab will study protein secretion in Gram-positive bacteria and its impact on host barriers & immunity.

Congratulations Uday!! We'll miss you, but I can't wait to see all the fantastic work to come out of the Tak lab

Thrilled to share the final version of my postdoc project, out today in nature! We investigated the Bil system – a ubiquitin-like antiphage defense system – and discovered a new defense mechanism! More info in the thread below 👇 nature.com/articles/s4158…

If you're interested in learning even more about the Bil system, check out this amazing structural study by Lydia and Qiaozhen from Kevin Corbett's lab, which was also published in nature today! nature.com/articles/s4158…

Out today in nature! I am thrilled to share our work on the PARIS immune system in its final published form. Huge thanks to my mentor, Kevin Corbett Kevin Corbett, and my teammates. See the thread below in comment section for a quick summary! nature.com/articles/s4158…

Very sad news for the cyanobacterial community. Our colleague Jeff Cameron passed away unexpectedly last week. He was a brilliant scientist and a very friendly person Please, consider donating to help his family in this hard moment gofundme.com/f/contribute-t…

Delighted to share our work developing an mRNA vaccine for C. difficile, published today in Science Magazine. This study with The Drew Weissman Lab was co-led by two truly amazing scientists: Alexa Sem from the Zackular lab and Mohamad-Gabriel Alameh (now at CHOP Research)! science.org/doi/10.1126/sc…