SOCRATES trial is now open for enrolment at Cabrini, Melbourne and is testing if taking a statin can prevent heart disease in patients with #melanoma treated with ICIs. This treatment could improve long-term outcomes and survivorship. masc.org.au/socrates/ Monash Victorian Heart Institute

NEW: Cardiac MRI utility for Ibrutinib Cardiotoxicity jamanetwork.com/journals/jamao… *Cardiac injury (fibrosis) is prevalent, and predicts future cardiotoxic events in cancer patients* Thanks to JAMA Oncology for publishing this work. #CardioOnc #hematology #CLL #Ibrutinib #WhyCMR

#Exclusive: Immunotherapy could be a game-changer for melanoma patients, but the life-saving treatment gives them with a greater risk of heart disease. Melbourne researchers hope a simple cholesterol-lowering pill could reverse the risk and save hundreds of lives | Caitlin Dugan

Glad to be part of the SOCRATES trial to improve🫀health in patients with #melanoma. We’re open for recruitment and looking for sites - tele-trial options are available. Please reach out or share with anyone who may be interested! Steve Nicholls Monash Victorian Heart Institute Melanoma and Skin Cancer Trials (MASC Trials) #CardioOnc

COORDINATE cluster RCT in 43 clinics across the US: - n=1049, T2DM + ASCVD. Age 70, 17% Black. - Multi-faceted intervention: QI | audit & feedback | education - Endpoint: Prescription @ 12mo: high-intensity statin + RAASi + SGLT-2i/GLP-1RA: - 14.5 vs. 37.9%, p<0.001

Reperfusion criteria used to determine success of fibrinolysis for STEMI may miss up to 9% of occluded culprit arteries. Time to rethink the criteria? Or have lower threshold for early cath with #RadialFirst? Monash Victorian Heart Institute Derk Pol Adam Nelson Steve Nicholls asiaintervention.org/article/diagno…

Patients receiving immune checkpoint inhibitors for cancer routinely have their BP checked when they attend for treatment. Could we be repurposing this for hypertension screening? nature.com/articles/s4137… Steve Nicholls Adam Nelson Prof. Eva Segelov Monash Victorian Heart Institute #CardioOncology

Prevention is key this #HeartWeek! 🫀 Monash Victorian Heart Institute and Monash Health visited State Parliament, conducting Heart Health Checks with Novartis and Wesfarmers Limited Mary-Anne Thomas MP MP received her heart check and spoke with Steve Nicholls about the importance of regular screening.

Can we prevent #HeartDisease after #Cancer? 🫀🎗️ Cardio-oncology is a new field born out of the necessity to address the increasing burden of heart disease among people with, or who have, survived cancer. Dr Sean Tan explains in Monash Lens: bit.ly/462rZW2

Just accepted in JACC: Asia JACC Journals our paper examining Asia-Pacific Investigators and Asian Enrollment in Cardiometabolic Trials between 2011-2020 Adam Nelson Yeo KK Steve Nicholls Daniel Scherer Carolyn Lam Chanchal Chandramouli Chris Wong

I was watching Lord of the Rings last night and realized there are many parallels with academia! A thread 🧵👇

The SOCRATES trial is now open at Latrobe Regional Health, led by site PI Dr Bhavini Shah. Eligible patients can access this trial without travelling to Melbourne. SOCRATES is testing if taking a statin can prevent heart disease in #melanoma patients. masc.org.au/socrates/

The SOCRATES clinical trial has a new site open! Led by the Monash Victorian Heart Institute and Melanoma and Skin Cancer Trials (MASC Trials) team, SOCRATES investigates whether taking a statin can prevent cardiovascular disease in melanoma patients. More: masc.org.au/socrates

Let’s go CommBank Matildas! Most nerve wrecking but easily best live match I’ve seen FIFA Women's World Cup #TilitsDone

🌞 SOCRATES trial 🔍 Testing whether a common cholesterol-lowering drug can prevent heart disease in #melanoma patients who have been treated with #immunotherapy. 👫 180 melanoma patients. 🌏 12 sites across Australia. 👉 masc.org.au/socrates/ Monash Victorian Heart Institute Steve Nicholls

Excited to share our data on ASCVD events among cancer patients treated with ICIs CV risk factors are commonly undertreated and should be targeted to improve cancer survivorship #cardioonc Steve Nicholls Prof. Eva Segelov Adam Nelson Monash Victorian Heart Institute sciencedirect.com/science/articl…

#CardioOncology is a collaborative field but discrepancies in guidelines used by each stakeholder involved in #CardioOnc care can lead to differences in cardiotoxicity Dx and Rx Much work to be done to unify our approach in Aus Steve Nicholls Monash Victorian Heart Institute sciencedirect.com/science/articl…

Many practical challenges affect ASCVD prevention in patients with cancer treated immunotherapy. Huge scope for opportunistic screening and implementation research in #CardioOncology Steve Nicholls Prof. Eva Segelov Adam Nelson Monash Victorian Heart Institute European Society of Cardiology Journals doi.org/10.1093/eurjpc…

Patients with HFrEF have ⬆️ incident cancer but undergo ⬇️ cancer screening than the general population (despite expressing interest). Should we include cancer screening in HFrEF programs? japscjournal.com/articles/cance… #cardiooncology #reversecardiooncology Monash Victorian Heart Institute

Routine preprocedural fasting for #PCI may not be necessary for all. With low rates of procedural intubation, targeted fasting for high-risk groups may be a better approach. #AHAJournals Megan Herson Sean Tan MonashHeart Monash Victorian Heart Institute ahajrnls.org/4ge8ePj