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Story time: Nearly one year ago, the Manifest Summer Camp team reached out to me and said "hey can you run a trading bootcamp at summer camp people might like it" and I said "ok sure whatever" (1/n)

And yet, a biotech founder would be lucky to own 12% of the company by the time the first human takes their drug candidate in a trial! You'll often see them keep a board seat & a bit of moral suasion, but it's rare to see a clinical-stage biotech with a founder truly in control.

Guys, my co-instructor for this June's trading bootcamp David Holt 🌴 is as thoughtful as he is hilarious, and y'all should jump at the opportunity to learn how to think like a trader from him! (and me, and Ricki Heicklen, ofc) arborsummer.camp/branches/tradi…

People in the limit are constrained by incentives and laws and etc. In the limit. But this works because that’s the exception handler in a world where most people want to do good and are trying. People care first, obey second.

Vega Shah Also this new podcast by Ross Rheingans-Yoo🔸, ‘Development and Research’ is diving into clinical trials and how unnecessarily wasteful the current system is, and what we can unlock by doing trials differently - open.spotify.com/episode/1lDsfv…

Ruxandra is doing God's work! While I think that the single greatest factor slowing down clinical research is lack of courage by companies in industry, ethics regulations that don't help patient safety play a role, too. If you have firsthand experience, please help her out!

Post-Mortem: $RCKT Trial Death & What It Means for Gene Therapy Rocket’s RP-A501 trial just detonated. One patient dead from capillary leak syndrome. FDA slapped a clinical hold. Cause? Likely a high-dose AAV9 (6.7×10¹³ GC/kg) + a mystery immunosuppressant aimed at

Nature is a pharmaceutical innovator. Ziconotide, derived from cone snail venom, treats chronic pain better than opioids. Alpha amanitin, a deadly mushroom toxin, is being used as a targeted cancer therapy. More examples abound. Our latest: TOXIC PROTEINS FOR DRUG DISCOVERY.🔻

The skalds and bards are the keepers of the oral sacred code of preliterate society. The lawyers and judges are the keepers of the written legal code of literate society. The hackers and engineers are the keepers of the executable source code of digital society.

You should be following Ricki Heicklen if you follow me Ricki is the smarter, younger version of me. She says things I think but don’t always have the words for despite saying too many words all the time.

PYOL (provide your own liquidity) party is happening tonight at Lighthaven in Berkeley you offer up bespoke items for imaginary currency and use that imaginary currency to bid

Two ways philanthropies fail to be good stewards of their assets: - (rare but sometimes egregious) paying people too much - (common) paying people so little that they adversely select for talent

I really *cannot* express how excited I am for Saloni and Jacob's new podcast! *Five hours* on the development of the most-powerful drugs against the most- important pandemic of the modern era. I might as well be in heaven!