I'm very grateful for the funding for 1 PhD to work with me on SUMOylation. Orléans is a beautiful place, & we have a nice working environment, a lot of ideas, & great collaborators for chemical and cellular aspects. I'll do what I can to make it a good time for the student.

Thrilled to share our preprint on structure-based discovery and optimization of SARS-CoV-2 macrodomain (Mac1) inhibitors. We present several low- to sub-micromolar inhibitors and atomic SAR thanks to >150 crystal structures! biorxiv.org/content/10.110…

Many congratulations Ivan! Ivan Ahel (Ivan Ahel Lab) was elected today as a member of EMBO! Ivan is a Professor of Chemical Pathology Dunn_School (now @DunnSchool.bsky.social) and specialises in ADP-ribosylation #EMBOMembers #EMBO #LifeSciences Read more: path.ox.ac.uk/news/ivan-ahel… (written by Isaac Siu-Shing Wong)

Raff Lab LEAN Green Labs UK Environment @ Oxford Jordan Raff Dunn_School (now @DunnSchool.bsky.social) University of Oxford Thank you Dunn School of Pathology Green Group, the Dunn_School (now @DunnSchool.bsky.social) members & thefacilities (WorkshopWashingUp, StoresPurchasing,IT, Admins) for your support. Could not have done without you all! Jo Palmer Martin Smith Natalie Marion Schuller Lilli Hahn Anton van der Merwe @WilliamSiwJames Environment @ Oxford

It was auch a pleasure and honour working with you and the team on this exciting project! biorxiv.org/content/10.110…

Happy to see the study on the Streptomyces coelicolor DarG homologue published CSBJ! Great collaboration with Andrea Hloušek-Kasun and Petra Mikolčević from Andreja Mikoč Lab revealing the mechanism of the hydrolysis of ADP-ribosylated thymidines! sciencedirect.com/science/articl…

Many thanks to Somerville College Somerville College and Philip Poole Rhizosphere Lab for the so lovely and warm welcome today! Very proud and really feeling honoured about joining Somerville College as a Fulford JRF!

Our discovery of SARS-CoV-2 Macrodomain inhibitors is now published in PNASNews!!! 🎯 160 hits identified through computational fragment-linking and virtual screening 💎 152 Xray crystal structures at atomic resolution pnas.org/doi/10.1073/pn…

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I learn new words with Wordle:-) @Ra_MicroSci Wordle 593 5/6 ⬜🟨⬜⬜⬜ ⬜🟩⬜⬜⬜ ⬜🟩🟩🟩⬜ 🟩🟩🟩🟩⬜ 🟩🟩🟩🟩🟩

Our discovery of more SARS-CoV-2 NSP3 Mac1 inhibitors is now published MDPI! An absolute highlight was that the antibiotic (and FDA-approved drug) aztreonam targets the macrodomain! All to read in doi.org/10.3390/pathog… Brennan Group Daren Fearon Ivan Ahel Lab

Had a great time performing an XChem screen this week at Diamond! Allowing me to work with the Shifter and the Echo which are among my most favourite instruments:-) Thank you XChem team!

I’m super excited to share another piece of my PhD work, delving deep into the PARP1/HPF1 signaling pathway in DNA damage. cell.com/molecular-cell…

I remember this day so well... what a huge honour it has been for me to meet His Majesty King Charles III in 2013 at St Stephen's House St Stephen's House... simply unforgettable moments

I'm so happy to finally share with you our latest research revealing how ADP-ribosylation controls the DNA damage response in Drosophila! 🪰🧬 Thanks to the fantastic team! Ivan Ahel Lab Nielsen Lab Osamu Suyari Antonio Ariza Dunn_School (now @DunnSchool.bsky.social) nature.com/articles/s4146…

René Bærentsen / Rene Baerentsen presenting his work on T6SS #ETOX in beautiful Crieff. Thanks to organisers for putting together such a great meeting

Thank you #ETOX 2023 for the opportunity to present our DarTG work and the really fantastic time!

This month the Dunn_School (now @DunnSchool.bsky.social) cleaning team wins the Support Staff Sustainability Award presented by Marion Schuller Kerryanne & Paul from Ivan Ahel Lab & Hassan Lab organisers of the Aug Dunn Drinks. They've played a crucial role to help us manage all types of lab & office waste.