7 minute Cyclizine Briefing Abuse potential & availability to purchase from pharmacies by Greater Manchester team gmmmg.nhs.uk/wp-content/upl…

👇💯 Other 7 minute briefings on 1) Nitrofurantoin 2) Tramadol and Warfarin Interaction gmmmg.nhs.uk/guidance/seven… NHS Greater Manchester Regional Drug & Therapeutics Centre GMMMG Thank you to everyone involved in the development - GM IPMO Meds Safety Group

Pregnancy Prevention Programme for topiramate gov.uk/drug-safety-up….

📣Our medicines monitoring tool summarises recommendations and guidance to help you develop individualised patient monitoring plans📣 This month we updated advice on levothyroxine. To access the tool click⬇️ sps.nhs.uk/home/tools/dru…

💊Opioids + immunosuppression💊 Some opioids (especially morphine, methadone, and fentanyl) are immunosuppressive, reducing natural killer cell activity and neutrophil chemotaxis. Four epidemiologic studies link prescription opioids to an increased risk of serious infections.

Gastrografin is the go-to water-soluble contrast for treating adhesive small bowel obstruction (ASBO). Each 100 mL has 10g sodium diatrizoate & 66g meglumine diatrizoate (osmolarity: 2150 mOsm/L). It works by drawing water into the bowel, reducing edema, and boosting muscle

All opioids act directly on blood and tissue cells to release histamine, which may produce flushing, tachycardia, hypotension, pruritus, and bronchospasm. Histamine release is greatest with large doses of morphine, while fentanyl, hydromorphone and remifentanil release little

🚨 SAFETY FLASH with UKCPA! 🚨 Pabrinex® Shortage. IV Pabrinex® will be out of stock from August 2024. See the full SF with links🔗: tinyurl.com/SF198 For all our safety flashes and news alerts: rcem.ac.uk/safety-3/#safe…

Our Self-Administration of Medicines policy has been highlighted by Parkinson's UK, as part of a new resource for professionals who are developing policies to improve the delivery of time-critical medication. View the guide - zurl.co/G0gT

Methadone's  analgesic duration is much shorter than it's anticraving effects when used for opioid use disorder (6 to 8 hours versus >24 hours respectively). When managing acute pain in a patient established on methadone for opioid use disorder the once daily maintenance dose of

A tragic death bbc.co.uk/news/articles/… Large volume LA infiltration (by a surgeon) now commonplace joint replacement, plastics & vascular surgery Falls between stools - who is the prescriber - who is responsible for preparation - who is responsible for complications Coroner's

Finally got round to publishing something 🙌 pharmaceutical-journal.com/article/ld/und…

🚨SAFETY FLASH 🚨 Glycerol Toxicity from Slushies Can present as nausea, abdominal pain, headache, drowsiness and profound hypoglycaemia. See the full SF with links: tinyurl.com/ytsm3yjt For all our safety flashes and news alerts: rcem.ac.uk/safety-3/#safe…

Do you run a UKMI patient helpline? Do you know what's most important to your potential callers, esp those who don't call in the end? Our new paper will tell you - extended opening hours & quick answers, but other things matter too. doi.org/10.1080/205232… 1/2

Liquid Vitamin & Iron Supplements in Neonates & Children. Latest NPPG position statement gives guidance on use & will be helpful in navigating shortages. It also has a link to a summary of liquid & chewable/soluble tablet multivitamins available in the UK nppg.org.uk/vitamins/

BIG THREE POINTS ❤️

THIS TEAM ✊

Statement made.

A special end to a special night 🫡

Three modes of organising for improvement: (1) Doing things well (2) Doing things better (3) Doing better things An organisational improvement strategy should focus on all three. Many organisations currently are overfocussed on (1) & (2) and under focussed on (3). This is risky