Los invito a la conferencia “Biología de sistemas de los trastornos neurodegenerativos” con la que inicia la serie: Avances Científicos Mexicanos. Una estrategia para dar a conocer el desarrollo y la innovación en diversos campos de la ciencia en México desde el Conahcyt Consejo ➡️1/2

Fully-funded 4-yrs #PhD in #DataScience for #biology & #medicine , Human Technopole (Milan) + SISSA (Triest), no restriction on nationality. DATA+THEORY to fight diseases.
Apply now, end Feb 17th!
-> datascience.sissa.it/apply
#LifeSciences #MachineLearning #datasciencejobs

nih.gov/news-events/ni…

bigthink.com/health/alzheim…

the-scientist.com/news-opinion/a…

our work in The Scientist

thetimes.co.uk/article/breakt…

📢 Open computational postdoc position in my team Human Technopole

🎯 Our goal is to unravel mechanisms of gene regulation in human lymphocytes using multimodal single-cell technologies

🙏 Please share! #hiring

➡️careers.humantechnopole.it/o/postdoc-in-c…

About 1 in 5 of us have an APOE4 gene variant, the #1 genetic risk factor for Alzheimer's disease. But the mechanism for brain injury was a mystery, now getting unraveled (cholesterol processing by oligodendrocytes) nature.com/articles/s4158…
@nature
nature.com/articles/d4158…

Amazing story from my colleagues in the Tsai Lab MIT Picower Institute on the impact of APOE4 onto myelination! From postmortem human brain snRNA-seq to iPSC models to humanized mice, they really pulled all the stops! 👏🏻👏🏻👏🏻

nature.com/articles/d4158…

Many thanks to Karl Carlstrom and Goncalo Castelo-Branco for their perspective on our new paper in nature in this News & Views nature.com/articles/d4158…

Happy to share our latest work demonstrating how APOE4 impairs myelination through cholesterol dysregulation in oligodendrocytes - out today in nature. Honor to work with such a great team Li-Huei Tsai, Joel W. Blanchard, Leyla Akay, Djuna von Maydell.
nature.com/articles/s4158…

How does APOE4 affects human brain in #Alzheimer ’s disease? The new paper on nature by our Jose Davila Velderrain and colleagues at Massachusetts Institute of Technology (MIT) Broad Institute Harvard University led by Li-Huei Tsai, paves the way for the development of novel therapeutic strategies for AD

humantechnopole.it/en/news/how-ap…

I am so excited to share my first first-author paper, out today nature!!

So thankful to work with three other amazing first-authors Joel W. Blanchard Jose Davila Velderrain and Djuna von Maydell, and an inspiring team lead by Li-Huei Tsai 🤩🔥

nature.com/articles/s4158…

Honor to work with co-authors Li-Huei Tsai, Leyla Akay, Djuna von Maydell, Jose Davila Velderrain
nature.com/articles/s4158…

Today in nature we show that cholesterol dysregulation in oligodendrocytes of Apoe4 carriers impairs axonal myelination. Cyclodextrin ameliorates the defects. Proud of lead authors Joel W. Blanchard, Leyla Akay, Djuna von Maydell, Jose Davila Velderrain picower.mit.edu/news/alzheimer…

Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration science.org/doi/10.1126/sc…

happy to have collaborated in this great project highlighting the inflammatory potential of damaged neurons with Gwyneth Welch and Li-Huei Tsai

I’m really looking forward to our two-day online symposium Oct. 5-6 where fantastic colleagues will discuss crucial research on neurodegeneration, #DownSyndrome and their intersections. You can register now to join us! eventbrite.com/e/glial-and-ne… Aging Brain @ MIT Alana

Are you a bioinformatician or computational biologist with a knowledge of #omics techniques?

Join our BrainOmics 5-days course to learn key computational tools for the analysis of single cell #multiomics datasets in #neuroscience 👉 humantechnopole.it/en/ht-course-b…

Ketogenic diet uncovers differential metabolic plasticity of brain cells science.org/doi/10.1126/sc…