NEW! This REVIEW examines how the maternal gut #microbiome in pregnancy influences the developing immune system nature.com/articles/s4157…

Integrating the gut microbiome and pharmacology | Science Translational Medicine science.org/doi/10.1126/sc…

Thrilled to have been part of this collaborative project from the International IgAN Network Research Group on histologic and clinical factors associated with kidney outcomes in IgA Vasculitis nephritis Sean Barbour Agnes Fogo fernando fervenza

🚨 Using microangiopathy to complement MEST-C in IgA nephropathy 🫘 Microangiopathy: 📉 Correlates with poor renal outcome 🔬 Independent from MEST-C score 👀 Check out the full paper here 👉 doi.org/10.1093/ckj/sf…

Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia - ⁦Cell Host & Microbe⁩ sciencedirect.com/science/articl…

Beating #KidneyFailure needs #RareDisease cures. @RenalRaDaR data out today reveals a staggering 28x higher 5-year kidney failure risk in 28k people with #RareKidney diseases c/w 2.8 million with #CKD. Trajectories in 28 diseases included for reference tinyurl.com/yvybsvx2

Microbiota species impact their host in a strain-specific manner through differences in their ability to bind human proteins

An interesting new microbiome study in Science Translational Medicine, by Gleeson and colleagues science.org/doi/10.1126/sc…

Very pleased to see this paper on the role of the gut microbiota in IgA nephropathy published in Science Translational Medicine! It was a pleasure to contribute to this study coordinated by R Monteiro and James Gleeson! science.org/doi/10.1126/sc… Inserm Sorbonne Université Université Paris Cité #Thread 1/11

When usually helpful bacterial partners go rogue, they can turn our body's defenses against us. That story, an update on the avian flu infecting cows, and more of the best from Science Magazine and science in today's #ScienceAdviser: science.org/content/articl…

Studying mice and patient samples, scientists find that the #microbiome member #Amuciniphila may spark IgA #nephropathy by deglycosylating IgA1, generating self-antigens that cross into circulation and kidneys and trigger autoimmunity. scim.ag/6tB

Thanks to Nature Reviews Nephrology for highlighting our work on the microbiota in IgA nephropathy recently published in Science Translational Medicine. nature.com/articles/s4158… science.org/doi/10.1126/sc…

My favourite Mícheál Ó Muircheartaigh quotes: "Seán Óg Ó hAilpín. His father's from Fermanagh. His mother's from Fiji. Neither a hurling stronghold." "The stopwatch has stopped. It’s up to God and the referee now. The referee is Pat Horan. God is God." "Teddy McCarthy to John

Nature research paper: In situ targeted base editing of bacteria in the mouse gut go.nature.com/3VW8iuJ

.ProgressIreland's first plan is about infrastructure. Ireland is about to splurge on infrastructure. But we’re already on the wrong track. Unless we change track, these projects will be slower and more expensive than they need to be. 🧵... progressireland.org/to-save-up-to-…

Good controls make good science. Thank you to Nicola M. Tomas et al. for clarifying their anti-nephrin auto-antibody data with further experiments in this week's NEJM.

The bacteria in your gut depend on where you are in the social network. And the microbes within us treat our social networks as the extended environment in which they thrive. They can spread from person to person. New #HNL work out today in nature. 1/