We can now obtain subcellular maps for both RNA and protein in the same experiment and show the dynamic changes in location of both in the unfolded protein response. Introducing LoRNA (the LOPIT for RNA) biorxiv.org/cgi/content/sh…

Genome editing owes a huge debt to genome sequencing With efforts like Human Cell Atlas, we’re sequencing cells like mad. What is the "Cas9" of single cell? With Omar Abudayyeh Fei Chen Lab: RADARS, for programmable cell-specific sensing/expression biorxiv.org/content/10.110… 🧵👇

Today’s experiment. The problem of having positive controls in cooking is they frequently overshadow the ambitious young upstarts. Pistachio wins!

Brillant Adam Grant

Björk, still on the bleeding edge after so many decades! Keeping some of her magic…#bjork

My husband is learning Farsi and his first sentence was a rap about the greatness of rice which basically sums up Persian culinary taste #tahdig

Small but mighty! This is a video of a killer T cell of the immune system destroying a monstrous ovarian cancer cell. I recently captured this data on a spinning disc confocal microscope.

CRISPR-based genome editing has been transformative, but insertion of large sequences requires DNA damage machinery How can we efficiency place DNA cargos anywhere in the genome? Today we report on PASTE, out in Nature Biotechnology w/ Omar Abudayyeh Massachusetts Institute of Technology (MIT) nature.com/articles/s4158… 1/🦃