Not all hybrid immunities are created equal; compared to those are are first infected then vaccinated (I-V), children who are first vaccinated then infected (V-I) are better protected against future COVID infections. thelancet.com/journals/lanch…

How cross reactive your T cells are to other coronaviruses after exposure to one of them depends on your HLA type

An honour to now be counted as a variant from this lineage 🤓

Commentary: Singapore’s dengue problem won’t go away without a vaccine Shirin Kalimuddin Duke-NUS Medical School Singapore General Hospital (SGH) channelnewsasia.com/commentary/sin…

Congrats Melissa Ng and thanks for the Tweetorial! Loved the movie especially 🤩

While defective TLR7 signalling can be associated with severe COVID-19, overactive TLR7 signalling can cause lupus! Inborn errors of immunity illustrate the fine balance that is required for proper immune functioning 🤓

Typhoid conjugate vaccine has promising vaccine efficacy of 78.3% over 4 years, but wide confidence interval in under-2s warrants more trials enriching for this vulnerable age group thelancet.com/journals/lance…

Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore - The Lancet Microbe thelancet.com/journals/lanmi…

Giving vax #2 in contralateral arm results in sustained benefits in antibody levels up to 1 year post vaccination 🤯 cost-effective vaccination policy to adopt? jci.org/articles/view/…

217 covid vaccines (mainly mRNA) in a single individual - no adverse events, no immune anergy, adaptive immune responses intact 🫨🫨 thelancet.com/journals/lanin…

This International Women's Day, we spoke to our staff and asked them to share who their female role models are and how they've inspired them. To all the amazing women in our lives, we salute you! 🙆💜 #DukeNUS #IWD2024 #InspireInclusion

A successful APSID School on ‘Inborn Errors of Immunity’ at Tokyo, Japan today, organised by Prof. Hirokazu Kanegane and team! Fantastic cases, engaging discussions, and lots of collaboration.

RSV accounts for 33% of hospitalised LRTIs in under 2s, and causes a 3x increase in risk of recurrent wheezing compared to non RSV LRTI 😱 high time for vaccination, not just making a vaccine… thelancet.com/journals/langl…

Class II HLA explains up to 10% variance of antibody responses in African infant cohorts for pertussis, diphtheria and hep B vaccines! nature.com/articles/s4159…

Financial incentives works for Singaporeans, grad students, and obese teenagers 🤗

WFH in Nature! In an RCT, hybrid WFH improved retention without damaging performance. Perceptions about WFH improved after experimentation. The power of a well conducted experiment! 😎 nature.com/articles/s4158…

RSV vaccines highly effective against hospitalisation and ED encounters for older adults. Hopefully coming to children soon! thelancet.com/journals/lance…