Good news: an experimental drug that kills off old senescent zombie cells in the retina improved vision in 6 out of 8 patients 😮👏

In the last few years we discovered that bile acids are conjugated with other amines by microbes. See nature.com/articles/s4158… for initial discovery and kept dissolving them nature.com/articles/s4158…, nature.com/articles/s4158…, nature.com/articles/s4158… as did other labs

Hot news out of Northwestern CSB! Choi lab make human T-cells 100x better at killing cancer cells! Just out in nature : nature.com/articles/s4158…

Thanks to Ying Xi and Tiffany Hong for an insightful and thought-provoking discussion in Immunity of our recent paper in nature on the mechanisms of susceptibility of diabetics to respiratory infection! nature.com/articles/s4158… cell.com/immunity/fullt…

New work in Cell looking at dysbiosis, antibiotic-induced Clostria depletion and how high fat intake promotes sorbitol intolerance through impaired microbial sorbitol catabolism - take a closer look here sciencedirect.com/science/articl…

I am very happy to report that the years of work we put into studying the ecology and evolution of a single cryptic human gut plasmid is now nicely summarized in a paper that just appeared in Cell: sciencedirect.com/science/articl… Here is a 🧵 to cover some take home messages.

…continuing with an inspiring talk by Yotam Cohen Yotam Cohen ElinavLab on some new and unexpected host-microbiome interactions impacting common human diseases. Great job Yotam!

If you enjoy bile acids, then this will be a fun read and a resource for you. It shows that we can begin using untargeted metabolomics big data mining using a mass spec query language to discover new molecules in animals and humans. cell.com/cell/fulltext/…

🚀Delighted to announce our recent publication in Science Magazine! We've unveiled novel Ruminococcal species🦠in the human gut, proficient in cellulose degradation🌾and finely tuned to our evolutionary journey.🔬Dive into the key findings with us. (1/9) bit.ly/3wUX80G

WomenPower ElinavLab !

Yesterday, the women of Elinav Lab gathered for a succulent workshop led by Hadas from Kibbutz Erez, exploring resilience and beauty in these superhero plants thriving in tough conditions. Thanks, Hadas, for the inspiration! 🦸‍♀️💪🌿 🪴#SucculentWorkshop #WomenInScience

Bringing precision nutrition home Selected oral presentations: ⁦Yotam Cohen⁩ ⁦Julie Gervis⁩ ⁦Annalisa Giosuè⁩ and Keyong Deng #PNF2024

We are looking for exceptional MSc and PhD students! 👩‍🔬🧪🔬🧑‍🔬🧫💩 If you're interested in exploring the interface between gastrointestinal tract immunity and the microbiota in various diseases and combining basic science with NGS in the best environment possible - send me a DM

I am very happy to share that I was awarded the 2024 Sidney & Joan Pestka Post Graduate Award from the International Cytokine and Interferon society for our endeavours into the mechanisms of diabetes and lung infection. cytokinesociety.org/samuel-p-nobs-…

Is it true that gut-brain signals after consuming ultra-processed foods high in fat+sugar cause exaggerated dopamine release in human brain reward regions akin to what you'd expect from addictive drugs?? The answer may surprise you!!💡🧠 Our latest work from Kevin Hall 's lab!

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

It is a great pleasure to announce today the launch of the NobsLab! Located at the University of Zurich, we will study microbiome-immune interactions and how they regulate diseases of the lung, in particular infection and chronic inflammation.

1/14 Excited to share our new ElinavLab Microbiome & Cancer Elinav Lab at DKFZ Weizmann Institute paper Cell, championed (for 6 years!) by the amazing Rafael Valdés, Avner Leshem, Danping Zheng and twitter-less Alon Savidor. In this work, we’ve adopted into microbiome.. cell.com/cell/fulltext/…

Our study is out in Cell! Presenting a new way of analyzing gut proteins originating from diet, microbiome, and host. ElinavLab Eran Elinav Rafael Valdés authors.elsevier.com/c/1kTSbL7PXqS-O

Our study Cell finds healthy Canadians that consume a non-industrialized-type #diet can modulate their #microbiome, boost beneficial metabolites and improve their health. In just 3 weeks: LDL cholesterol ↓17% fasting glucose ↓6% CRP ↓ 14% cell.com/cell/fulltext/…