It’s been a big week- so great to have the opportunity to present our new study led by Yanxiang Meng & Katherine Davies with Peter Czabotar at FAOBMB2021 and ANSTO AUM21. We report the first human RIPK3 structure- alone and bound to an inactive MLKL conformer nature.com/articles/s4146…

James Murphy Yanxiang Meng Peter Czabotar FAOBMB2021 ANSTO Congratulations everyone great to see this out

WEHI researchers have visualised a human cell death complex linked to autoimmune & inflammatory conditions for the first time. The findings could help discover drugs that can target and suppress cell death by #necroptosis. wehi.edu.au/news/first-str…

Who hasn’t had issues cloning 😅 This project is based on a comic a friend shared with me. Unfortunately, the original comic appeared to be anonymous, but I’ll share it in an effort to attribute proper credit.

I am honoured to be the recipient of ASBMB Fellowship and Fred Collins Award. Thanks James Murphy Peter Czabotar Jarrod Sandow and amazing team that made this possible.asbmb.org.au/awards/yanxian…

Congrats to some legend ECRs Yanxiang Meng Chris Horne from my lab as well as Tess Malcolm and Jacinta Conroy on the ASBMB Fellowships #combio2022

Congratulations Yanxiang Meng on submitting your thesis! It was an absolute pleasure to complete our PhDs side by side 👨‍🔬 👩‍🔬

Fantastic talk from Chris Horne on the mysterious 'dark' kinases PSKH1/2 at the 88th Harden Conference: Beyond catalysis - Kinases and Pseudokinases 2022 Biochemical Society!

We are pleased to announce that our December #ACDS seminar will be presented by Dr Shuai Huang and Dr Sarah Garnish, both WEHI (Walter and Eliza Hall Institute)🤩 Join us via Zoom on Wed 7th Dec at 12pm AEDT (11am AEST) to hear these great speakers - our last seminar for 2022! DewsonLab James Murphy

A proud moment for #BiochemSocTrans - on the 50th birthday of the reviews journal Biochemical Society Portland Press Congrats to these stars from the @LorneProteins conference last week for their Anders Early Career Awards. Congrats to Yanxiang Meng Wint Wint Phoo Charles Bayly-Jones & Sam Ramesh

#Celldeath #research in Nature Communications: 2–3% of the global population carry a #MLKL gene variant that makes them less effective at slowing #necroptosis, which can lead to #inflammation and disease. Learn more: wehi.edu.au/news/when-cell… 🧵1/3

Excited to share our latest Nature Communications paper on how phosphorylation drives the activation of full-length MLKL by unleashing the killer 4HB domain in a teramer! Thanks to brilliant co-authors Sarah Garnish & Katherine Davies, collaborators, and mentors James Murphy Peter Czabotar

It was a pleasure to be invited to the #AUM2023 last week and hear about the amazing works done at ANSTO and ACNS. Thanks to ANSTO and the Australian Synchrotron for the honour of the Stephen Wilkins Medal and the instrumental support to my PhD.

Pseudokinases represent. Proud to see Sarah Garnish receiving the first of 2 Anders Early Career Awards to members of our lab tonight @LorneProteins Stellar presentation (as usual)!

Another proud moment with star postdoc Chris Horne from our lab presenting his @LorneProteins Anders ECR Award talk on our new work on CaM regulation of kinases. Magic Tones represent

Congrats to Sarah Garnish on the Anders Award @LorneProteins! Excellent talk on the mechanism of MLKL activation and its implications to human diseases. It was a pleasure to have worked together on these projects

Big congrats to WEHI’s Dr Sarah Garnish, a winner at last night’s Premier’s Awards for Health and Medical Research! 👏 👏 👏 “I really hope that one day our discoveries will help the thousands of Australians who live with inflammatory diseases.” Bravo Dr Garnish!

Glad to see this out😄 With Wayne Cawthorne, Andre Samson & James Murphy Looking forward to seeing more discoveries of how PTMs regulate protein shapeshifting during necroptotic cell death ☠️ Check it out here 👇 doi.org/10.1016/j.tibs…