Prof Gregg W Stone presented their ULTIMATE-DAPT trial in ACC. 24.

DanGer Shock Trial
#LBCT #ACC24
⁉️ will use of Impella in pt with STEMI+Shock ⤵️☠️
🫀355 pts, 79% male (where are the women??)
🫀primary endpoint☠️: superior for Impella
🎯 cost: more adverse events: bleed, limb ischemia, renal replacement tx, sepsis
📎 nejm.org/doi/full/10.10…

After 10 years to complete it, the DanGer-SHOCK trial showed that the routine use of a microaxial flow pump with standard care in the treatment of patients with STEMI-related cardiogenic shock led to a lower risk of death from any cause at 180 days than standard care alone.

The…

The PREVENT trial showed that preventive #PCI of focal non-FFR-positive plaques that are angiographically >50% & have evidence of vulnerability on intravascular imaging along w/ OMT is superior to OMT for clinical outcomes at 2 years.

Read more: bit.ly/3xuHWrl

#ACC24

INOCA in Long COVID syndrome. First evidence, most likely due to affinity of SARS-CoV-2 for endothelial cells. Stratified Tx improves angina. Just published in JACC Intv. Access: authors.elsevier.com/a/1iubV_i2X-Os…. PCRonline 🫀 IdISSC, IIS del Hospital Clínico San Carlos Complutense INOCA INTERNATIONAL JACC Journals

Differential Impact of Fractional Flow Reserve Measured After Coronary Stent Implantation by Left Ventricular Dysfunction | JACC: Asia jacc.org/doi/10.1016/j.…
William Fearon NICVD INTERVENTIONAL CARDIOLOGY NICVD RTHahnMD Ziad Ali Ramzan Zakir Barry Uretsky American College of Cardiology SCAI Now TCTMD Cardiovascular Research Foundation

1/4 Just publ in the Lancet our updated network meta-analysis of imaging-guided (OCT or IVUS) vs. angio-guided PCI across the spectrum of CAD. With 22 RCTs and 15,964 pts this is the 1st study to demonstrate that imaging reduces all-cause death (by 25%), as well as all MI (17%).

I did #OCT to evaulate a lesion and found uncomplicated plaque with MLA of 2.9 mm2: is this lesion haemodynamically significant?
This new 502-lesions study evaluated by both #FFR and #OCT provided interesting information....
sciencedirect.com/science/articl…

The PROTECT III study focuses on a population of patients requiring prolonged mechanical circulatory support after Impella-supported HR-PCI, observing outcomes like complications and mortality, and emphasizing the need for tailored management strategies by specialized teams.…

Pretreatment with P2Y12 inhibitors in #STEMI - insights from the Bern-PCI Registry

This study sought to compare outcomes 📈📉 between patients presenting with STEMI before & after the recent ESC guidelines for the management of ACS recommendation against pre-treatment with…

A thorough understanding of study designs, populations, treatments, results, and limitations of trials testing P2Y12 inhibitor monotherapy vs. DAPT or vs. aspirin is required to consider adopting this treatment in clinical practice. This review addresses the use of aspirin-free…

Where are we with drug-coated balloons (DCB) in PCI? Five thoughts.

1) The use of DCB in patients with in-stent restenosis, especially of a bare metal stent, is well established and evidence-based (now also in the US).

2) Conversely, DCB use in de novo disease lacks compelling…

BCM Cardiology Waleed Kayani Mahboob Alam Musa A. Sharkawi Dr Shariq Shamim jedicath աǟզǟʀ.ǟɦʍɛɖ Mamas A. Mamas Timir Paul, MD, PhD, FACC, FSCAI, FAHA SCAI Now Sanah Christopher Jing Liu, MD Salik Nazir Evandro Martins F. MD Poonam Velagapudi Dr. Krzysztof Pujdak Osama Bisht Dr Imran Hanif Hashmi Hady Lichaa, MD, FACC, FSCAI, FSVM, RPVI Arslan Shaukat Tom Wilson Jeffrey Wilson, MD Bilal Iqbal Here are #IVUS images matched w MLA of the 3 LMs.

All 3 LMs w ~50% angiographic stenosis YET have a significant variability in IVUS MLAs

Teaching pt for #ACCFIT : Always IVUS when ANY doubt for LM, coz difference could be CABG versus nothing! #CardioTwitter #Cardiology

PADN has been approved

This research underscores the importance of intravascular lithotripsy (IVL) for the challenging issue of stent underexpansion due to heavy calcification. In this multicentre international registry, IVL showed to be both safe and effective, significantly improving lumen and stent…

Cost effectiveness analysis Work led by Andrew SP Sharp and his team showing an IVUS-guided PCI strategy was highly cost-effective over angiography alone amongst ACS patients undergoing DES implantation due to the medium- and long-term reduction in repeat PCI, death, and MI…

The REVIVED viability study is now out in print..
Extent of viable myocardium was NOT associated with patient outcomes.. but amount of scar was! JAMA Cardiology
jamanetwork.com/journals/jamac…

Optimal angiographic views for invasive coronary angiography: a guide for trainees
bjcardio.co.uk/2016/08/optima…
#CardioEd #CardioTwitter #Cardiology #Cardiogen

From the BIF-ARC consensus document, the MADS-2 classification of bifurcation stenting techniques. The upper panel shows the standard techniques, whereas the lower panel shows the “inverted” techniques. eurointervention.pcronline.com/article/defini…

At #heartlive at my old pci training centre discussing lms revasc. Absolute difference in cabg vs pci event rates from rcts at 5-10 yrs small. Neither cabg nor pci is definitive treatment for most pts- most will need further treatments. need to consider lifetime disease…