Congratulations to William Yang and colleagues UCLA Health on their paper published today in Neuron on the development of a new mouse model to shed light on #Huntingtonsdisease onset and improve targeting of potential therapies. Read here: uclahealth.org/news/ucla-heal…

Researchers at UCLA Semel Institute & @DGSOMUCLA led by X. William Yang have developed a mouse model that better recapitulates #HuntingtonsDisease, providing new clues & giving researchers a powerful new tool to test new therapies.

A genetically-tweaked Huntington's disease mouse model shows a tendency for the CAG repeat to grow, just like we see in humans with the mutation. en.hdbuzz.net/318

Today is the beginning of #HDAwarenessMonth. Stay with us during the month to hear from HD families and researchers. #HDAwareness #HuntingtonsDisease #Research

My lecture class on the "Making of Modern Ukraine" started last week. Video will be posted on YouTube a couple days after each lecture. youtu.be/bJczLlwp-d8

Mammalian Methylation Consortium unveils key findings: 1) Phylo-epigenetic trees, built on ultra-conserved cytosines, align with known phylogenetic trees - showing evolutionary pressures on epigenetics. 2) Methylation patterns linked to max life span differ from those tied to

Pan-mammalian epigenetic clocks are highly accurate across species, from mice to whales! 🐭🐋These clocks predict mortality risk, hinting at their value in preclinical studies. Epigenetic aging processes are evolutionarily conserved across mammals, intertwining aging and

Happy to share this paper led by fabulous postdoc Dan Wilton in collaboration with Kevin Mastro 🏳️‍🌈 X. William Yang and team. Highlights and Tweetorial to follow ..

Interesting new mechanism on RNA toxicity in HD through m1A modification of expanded CAG repeat and TDP-43 binding. Congratulation to Yinsheng Wang UC Riverside and collaborators!

Today, Dr. Monica Bertagnolli (Dr. Monica M. Bertagnolli) issued a statement reinforcing the value that NIH places on our relationships with Asian-American, Asian immigrant, and Asian researchers & their extraordinary contributions to advancing science. Link: nih.gov/about-nih/who-…

Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” laskerfoundation.org/winners/cgas-e… #Lasker2024 #LaskerLaureate