Way to go team! Facile transformation and dCas12a CRISPRi are big steps to precision fermentation in Clostridia William Rostain Tom Zaplana Chloé Baum @ettwiller pubs.acs.org/doi/10.1021/ac…

Thrilled to share this new paper from our lab. We show that Cas9 binds to hundreds of positions in bacterial genomes and can silence genes with as little as 4nt of complementarity between the guide RNA and the target. Nucleic Acids Res doi.org/10.1093/nar/gk…

Please RT: A funded PhD is available for cross-species design of resource-aware circuits. #PhD #synbio #resourceaware #crossspecies #biocomputing #circuits #pathways. Ioana Popescu INRAE Micalis Université Paris-Saclay @LifeSciencesUPS Details here: cellularcomputing.group/joinus/