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The Greenleaf and Pasca Labs are looking for graduate students and postdocs interested in perturbing transcription factors and chromatin remodelers in human brain organoid systems with an aim of quantitatively understanding drivers of normal human development. Email Will!

The Greenleaf and Gifford Labs are looking for graduate students and postdocs interested in perturbing transcription factors and chromatin remodelers in human heart organoid systems with an aim of quantitatively understanding drivers of normal human development. Email Will!

The Greenleaf lab is looking to recruit graduate students and postdocs interested in combinatorial cell state engineering. If you are interested combining multiplex perturbations and single cell readouts to "push" cells into target states, email Will!

Our human multipotent lymphoid progenitor paper is finally out! nature.com/articles/s4146… After revision, we added more in vitro validations of the lympho-myeloid potential of this HSPC population. Lots of thanks to Bendall Lab & William J. Greenleaf

The Greenleaf and Pasca Labs are looking for graduate students and postdocs interested in perturbing transcription factors and chromatin remodelers in human brain organoid systems with an aim of quantitatively understanding drivers of normal human development. Email Will!

The Greenleaf lab is looking to recruit graduate students and postdocs interested in combinatorial cell state engineering. If you are interested combining multiplex perturbations and single cell readouts to "push" cells into target states, email Will!

The Greenleaf and Gifford Labs are looking for graduate students and postdocs interested in perturbing transcription factors and chromatin remodelers in human heart organoid systems with an aim of quantitatively understanding drivers of normal human development. Email Will!

Our single-cell, pan-cancer analysis of open chromatin in human cancers, done in collaboration with TCGA and the Chang and Corces labs (among others including Illumina), is out in Science today. Congrats to Laksshman Sundaram and all authors! science.org/doi/10.1126/sc…

Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia! nature.com/articles/s4158…

Huge congrats to Howard! We will sorely miss him here at Stanford, but wish him all the best for this immensely exciting opportunity!

Our work using thermodynamic principles to link in vitro TF affinities and kinetics to single-molecule chromatin states in cells is now on bioRxiv! Amazing effort by first author juliaschaepe in William J. Greenleaf lab: biorxiv.org/content/10.110… Stanford University SciLifeLab Stockholm University [1/9]

Pleased to announce this latest work from the lab!