Did you know that severe inflammation leaves a lasting impact on our blood stem cells? Excited to share our pre-print where we identified an HSC subset that remembers past inflammatory stress, which is linked to human aging and clonal hematopoiesis! doi.org/10.1101/2023.0… 1/

Honored to be Co-I of dual #EHA2024 updates on Pelebresib+RUX 1L MF trial (#MANIFEST2) showing benefits over RUX alone on fibrosis, VAF, erythroid development, spleen, most symptoms Raajit Rampal, M.D.Ph.D. MorphoSys Novartis Atrium Health Levine Cancer Wake Forest Baptist - Comprehensive Cancer Center Wake Forest University School of Medicine

Prof Pemm showing TRANSFORMation of pt disease status with Rux + Navitoclax in MF HR Naveen Pemmaraju, MD #EHA24 #MPNSM improving pts lives

#EHA2024 #EHA24 #menin_inhibitors 1/3 Kuhn: summarizes menin inhibitors in clinical 🧵 1) In preclinical models showed synergy with FLT3i and BCL2i 2) menin inhibitors showing excellent response rates with Ven+HMA 3) Ziftomenib received breakthrough designation and

Excited to finally see published the collection on Haploidentical HSCT, which I was privileged to curate for Hematology, the official journal of the International Society of Hematology drive.google.com/file/d/12lT8G7… ASTCT Transplantation and Cellular Therapy Journal ASH Clinical News ASH

There is strong selective pressure for CH mutations in #HSC, as a way to attenuate the impact of inflammation and aging. Such a wonderful collaboration with paresh vyas and John Dick, driven by Asger Jakobsen Sven Turkalj Andy Zeng. MRC WIMM Princess Margaret Cancer Centre Research

William Osler Health System has joined University Health Network's Princess Margaret Cancer Care Network. This partnership between William Osler Health System and Princess Margaret Cancer Centre will enhance clinical expertise, research and education in our communities. Learn more 👇 pmcancercarenetwork.ca/princess-marga…

Pleased to share the final version of our Blood Advances paper on outcomes in pts w/ MPN-AP/BP in the current era of myeloid therapies! #mpnsm #leusm Yasmin Abaza Iyana Gross Hannah Johnston, MD See the tweet below for a breakdown thread ashpublications.org/bloodadvances/…

#iwMPN MDS 204 meeting. Great talks & discussions 💡 future of the MPN field | Ruben A. Mesa, MD Claire Harrison Andrew Kuykendall MD Mrinal Patnaik Chris Hourigan Lachelle Dawn Amer Zeidan MBBS,MHS ‏عامر زيدان Dr. Uma Borate: Associate Professor Aditi Shastri, MD Alex Rampotas J.J. Kiladjian Aaron Gerds MD, MS Emma M. Groarke #MPNSM Kristen Pettit

New paper in Blood Advances led by Tania Jain Vikas Gupta on donor types for allo-HCT in myelofibrosis #mpnsm ashpublications.org/bloodadvances/…

#mpnsm Vikas Gupta CIBMTR ASTCT Wael Saber — evolution of donor options over time for myelofibrosis…(ref:compare to Gupta etc al BBMT 2014). Perhaps timing and improving #ACCESS more critical than donor match?

Happy to share our new article on autopsy of acute leuk. A rare treasure of knowledge Pankaj Malhotra Amanjit Bal DrArihant@jain #leukemia Bridging the gap: understanding contemporary autopsies in acute leukemia by comparing ante-mortem and post-mortem profiles tandfonline.com/doi/full/10.10…

🚨 hot off the press 🚨 A (perhaps) underestimated aspect of CAR T-cell therapy: non-relapse mortality. Check out our new meta-analysis on this clinically relevant topic - out today in Nature Medicine ! nature.com/articles/s4159… Let’s take a deeper dive! Start 🧵

🎉Finally published🎉 Reduced intensity transplantation with busulfan or treosulfan is similarly effective in myelofibrosis While higher intensity led to worse outcomes Treosulfan should be used in reduced dose intensity🙏 #mpnsm AmericanJournalofHematology dx.doi.org/10.1002/ajh.27…

Was an honor and a pleasure to be part of this global consensus project! #MPNSM Claire Harrison ⁦J.J. Kiladjian⁩ ⁦Vikas Gupta⁩ ⁦Vikram Mathews⁩ ⁦S Koschmieder⁩ #johnmascarenhas #francescopassamonti ⁦#martinellis nature.com/articles/s4137…

rdcu.be/dNedg A global consensus on management of myelofibrosis; focus on challenges with cytopenia nature.com/articles/s4137…

🎉 Exciting News! 🎉 Join us for the 2nd Annual Allogeneic Blood and Marrow Transplant (BMT) Patient Survivorship Day at Princess Margaret Cancer Centre ! 🌟 This special day celebrates our resilient community of post-transplant patients, their dedicated caregivers, and the multidisciplinary

Incredibly excited to announce the official launch of our hematology education website - CBC Made Easy! Designed for all education levels, this website is a free tool to practice diagnosing various CBC abnormalities cbcmadeeasy.com

#SOHO2024 Presenting Princess Margaret Cancer Centre experience of using Gilt- combinations in R/R FLT3 AML. In this non-randomized study we provide enough evidence to suggest Gilteritinib combinations is a better bridge to ASCT than monotherapy AML Hub Mithun Abraham Prakash Jayastu Senapati Society of Hematologic Oncology (SOHO)

➡️Excited to share our recent review on unmet needs in SCT in myelofibrosis focusing on timing of transplant, peri-transplant spleen management and donor selection. Arjun D. Law 𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM Ashwin Kishtagari, MD Jayastu Senapati Raj Chakraborty Blood Cancer Talks link.springer.com/article/10.100…