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Endometriosis is a painful condition that affects many women worldwide. This year's IISc iGEM team is keen on finding a therapeutic solution. Read more about their efforts: kernel.iisc.ac.in/the-race-to-re… #IIScresearch

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (Katalin Kariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her

Super excited to present #Blush and with it expand the applicability of cryo-EM. We reconstruct one of the smallest complexes ever with cryo-EM. A 40 kDa protein-RNA complex. biorxiv.org/content/10.110… But how do we make sure we’re not overfitting? 🧵1/4

Happy to be part of this!

1/ I've been waiting too long to share this. variability refinement allows to refine an ensemble of PDBs in an ensemble of maps from 3DVA CryoSPARC or multibody ref. in @RELION. #cryoEM. Available in Phenix

A new version of AlphaPulldown by DingquanYu. Includes experimental support for multimeric templates in AlphaFold by Dmitry Molodenskiy and interface to crosslink-based modeling AlphaLink2 of Rappsilber laboratory github.com/KosinskiLab/Al…

Impressive results at 100keV from Chriss Russo group at MRC, LMB. Look at no. of particles, and micrographs and resolution achieved. A majority of the structures (7 of 11) extended to beyond physical Nyquist resolution. pnas.org/doi/10.1073/pn…

A new automated platform for cryo-EM/ET grids preparation. Great engineering by Papp Team - EMBL GR Instrumentation and collaborative EMBL effort to validate the approach. biorxiv.org/content/10.110…

CryoCycle your grids! Plunge vitrify & reuse clipped cryoEM grids. We show vitrified proteins & cells (thin areas), offering $10k+/yr in savings. Added benefits: simpler clipping, less grid damage, no frozen fingers, & no need for commercial plungers. biorxiv.org/content/10.110…

Really happy to have been part of this work!!! It’s finally out!!! Congrats Rishi Kumar Mishra for leading the work and the co-authors PRAFFUL SHARMA, Faisal Khaja Tarique, and supervisor Tanweer Hussain. Developmental Biology and Genetics IISc Bangalore #cryoem #ribosome

Excited to share the first preprint from my PhD!

Bit of a late post, but I had the incredible opportunity to attend and present my work at the Biophysical Society Annual Meeting this year! It was my first #BPS and also my first conference outside Canada. I got to learn from so many inspiring biophysicists doing amazing science!

Excited to share the first paper from my PhD!!!

Another exciting paper from my work at the Zeytuni lab in collaboration with Vahidi Lab@UofGuelph 🇨🇦 !

Thrilled to be part of these exciting projects!