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First ever engraftment and maturation of autologous iPSC-cardios post-infarct without immunosuppression (out to 14 months). Incredible bicoastal collab with Cindy Dunbar & Manfred Boehm’s team NIH NHLBI to pull this off—what a journey! ISCRM at UW UW Medicine

"The ability to deliver larger dystrophins bodywide has been a long-sought goal in the field and has the potential to transform gene therapy for muscular dystrophy."

Several common injuries seem to haunt women’s sports. Jenny Robinson, Mechanical Engineering at UW, is interested in designing better methods to help women athletes train to prevent and recover from injuries. More: washington.edu/news/2024/07/2…

Our new publication in Journal of General Physiology investigating mechanism of a novel myosin inhibitor! Michael Regnier MuscleX_Lab UW Center for Translational Muscle Research UW Bioengineering

Grateful for an AmericanSkinAssociation grant to support our work Simpson Lab @UWMedicine @DermatologyUW to understand how #keratinocytes mature via #autophagy to form the outer skin layers and how this is disrupted in thick, scaly #psoriasis plaques (image from DermNetNZ). americanskin.org/news/pr_202407…

Excited to share our human RA-gastruloid model in Nature Cell Biology! Early retinoic acid supplementation, followed by later Matrigel addition, robustly induces human embryonic morphologies and diverse cell lineages, including somitic, renal, cardiac, and neural cell types in

Many thanks to the LEO Foundation (LEO Foundation - LEO Fondet) for supporting our work on the cell biology of skin immune cells!

Congratulations Brizzia Munoz Robles!

Want to photorelease proteins from biomaterials w/o exogenous light? Use BRET! "Bioluminescence Resonance Energy Transfer (BRET)-Mediated Protein Release from Self-Illuminating Photoresponsive Biomaterials" is live J. Am. Chem. Soc.! 📜:doi.org/10.1021/jacs.4… Congrats Teresa Rapp!

We're just ONE WEEK AWAY from the Society for Biomaterials (SFBiomaterials)'s inaugural Northwest Symposia here in Seattle University of Washington on Sept. 19-20, 2024! Exciting speakers, posters, panel, social, & networking! Registration is still open! biomaterials.org/2024-regional-… Come join the fun!

Join us this Wednesday, Sept. 25th at 3pm EST for a #TissueTalk with University of Washington Prof. Cole DeForest on “User-programmable hydrogel biomaterials to probe and direct 4D stem cell fate.” See you there: bit.ly/tissuetalks

Postdocs nationwide: Applications are now being accepted for the 2025 Inclusive Leadership Workshop (May 5-8 in Seattle). No program costs. Hotel and lodging covered. Space is limited! #inclusiveleadership #diversityinSTEM shorturl.at/CZO2Y

The Sniadecki Lab and the UWDentalSchool have used a 3D modeling system, originally developed to measure the force of beating heart cells, to reveal insights about the cellular dynamics at work in the periodontal ligament. shorturl.at/UllPN

Researchers at ISCRM at UW and UC San Diego Bioengineering use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. UW Center for Translational Muscle Research RegnierLab UW Bioengineering shorturl.at/eGwFw

Calling all faculty candidates (postdocs, Asst Profs, senior grad students) - Apply to UW Bioengineering! Job ad at link below. If you are considering applying and have questions on the ad, please email or DM me. Come join us, UW is amazing! apply.interfolio.com/155240

Congratulations Kelly Stevens!

”David Baker, Demis Hassabis and John Jumper, your ground-breaking work in computational protein design and protein structure prediction has revolutionised these fields. It has opened up completely new possibilities to design proteins that have never been seen before, and we now

Our paper in Biophysical Journal on cardiac muscle parameter estimations! Work led by Travis Tune from UW Center for Translational Muscle Research in collaboration with Jen Davis and Tom Daniel! UW Bioengineering ISCRM at UW UW Dept. of Laboratory Medicine and Pathology 🔬 Bayesian estimation of muscle mechanisms and therapeutic targets using... sciencedirect.com/science/articl…

We got the cover!!

A new paper by Justin Daho Lee, uwberndtlab, Molecular Engineering & Sciences Institute, UW Bioengineering, ISCRM at UW, NAPE Center highlights far-red chemigenetic H2O2 reporter oROS-HT635, which enables detailed insights into the intricate intracellular and intercellular H2O2 dynamics nature.com/articles/s4158…