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Mass spectrometry is used for ~ 150 x 10⁶ clinical tests / year. ⬛️ It provides solutions that are faster, better, cheaper, and more robust than competing methods. How many clinical diagnostic assays are performed annually by using NGS methods?

This is such great news. I can hoenstly say that I do not know anyone in the world more deserving of this than Brady Lab. An incredible scientist and an incredible human being.

I made a few more tutorial videos on the newest versions of DIA-NN & Fragpipe for those new to the software. Because why pay us when you can do it yourself right? youtube.com/@UCDavisProteo…

Curious how one becomes a "bona fide" researcher. Is there a o-link probe for this? I'd watch out for hook effects on this one. Maybe you could be so "bona fide" it comes back negative?proteomicsnews.blogspot.com/2024/07/41000-…

New preprint! Our first with our own single cell proteomics data! biorxiv.org/content/10.110… A tweetorial:

One of the more useful and free! tools I have found to rename a bunch of files in windows! learn.microsoft.com/en-us/windows/…

Since moving to DIA I have almost stopped looking at MS2 spectra entirely, except to marvel on how it pulls ions out of that complex mess. Such a change, us dumb humans can't interpret MS2 spectra any more 😭

LAST CALL ❗ Submit your work to our 2024 Special Issue on Single-Cell Omics Research, curated by Prof. Nikolai Slavov & Theodore Alexandrov. Deadline to submit is July 31, 2024 ➡️ go.acs.org/ah3. #singlecellomics

This is legit insane . I always thought this was an okay journal too.

Don’t want to miss this one ! Leanne Wybenga-Groot will actually make sure we talk about…gasp… proteomics !

We are hiring two Research Fellows! 😁 (Spatial/SCP) and a general expert (qual/quant). $85-136k+17% Super (aka 401k). >13 mass specs, inc astral, cellenONE, robots, autobots, repeating pipettes inc tips. An amazing team 🥳 linkedin.com/jobs/view/3986… #proteomics #massspec

We were wondering why this proteomics data seemed to move around so much 🤔 ucdavis.edu/news/new-metho….

Looking for a sample preparation method for FFPE tissue proteomics and phosphoproteomics? Check out our latest paper which compares a range of deparaffinisation, rehydration and extraction methods. Link: pubs.acs.org/doi/10.1021/ac…

Why does my phone insist on changing denovo to senior . Maybe it’s trying to tell me something 🤔

Ben Neely 🇺🇦 We try look at all the raw data, BPI or TIC. I've also got a process that runs every 30 minutes and makes an image like the one attached for any new raw files across multiple machines. It can help look at a bunch faster cuz just an image file.

Hello twitter hive mind (yes I'm reminiscing about the good old twitter days ) I still haven't found a good cheap material I can use to test phosphorylation enrichment. My mouse liver is not great. What does everyone else use? Should be complex & have lots of potential phos

Listen to three of the next generation of proteomics scientists as they share their research from US HUPO 2024! Tuesday, September 27 at 11:30 AM PST | 2:30 PM EST. Learn more and register at ushupo.org/Webinars. Sponsored by US HUPO's ECR. #ProteomicsResearch #ushupo2024

I wish journals would require methods papers be reproducible by at least 3 labs before it can be published . Think of all the time and resources this would save !

We had another great Proteomics Summer Class this year!! Thanks to everyone who participated!! I have some very prelim data from 2024 & 2023 for the 3 sample prep methods we tested across 50 "newish" users . docs.google.com/presentation/d…

BREAKING NEWS The Human genome and proteome is larger than we thought. Human Proteome ISB