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Potential probiotics for marathon runners 😀

I am happy to share my latest work on osmotic stress in S. aureus as a preprint: High-throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus (MRSA) biorxiv.org/content/10.110…

Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA advances.sciencemag.org/content/6/47/e…

Please share while the PVL is in the making: a postdoctoral fellowship position is available in our lab starting July 1, 2021, to engineer Lactobacillus reuteri to selectively eradicate microbial pathogens. Send me an email [vanpijkeren a t w i s c dot edu] or DM if interested

Happy 4 year anniversary to the best interview of all time

Debaryomyces hansenii is a VERY common yeast in aged cheeses and other fermented foods. It has generally been considered safe for humans (and potentially even "probiotic"), but this work suggests possible problems for those with Crohn’s disease science.sciencemag.org/content/371/65…

Class A PBPs: it is time to rethink traditional paradigms dlvr.it/RvWCCN

c-di-AMP, a likely master regulator of bacterial K+ homeostasis machinery, activates a K+ exporter pnas.org/content/118/14…

Pleased to share our latest work on c-di-AMP with great collaborators Esteban Marcellin and Zhao-Xun Liang Cyclic di-AMP Oversight of Counter-Ion Osmolyte Pools Impacts Intrinsic Cefuroxime Resistance in Lactococcus lactis mbio.asm.org/content/12/2/e…

Population dynamics of microbial cross-feeding are determined by co-localization probabilities and cooperation-independent cheater growth The ISME Journal by Rinke van Tatenhove-Pel et al with Herwig Bachmann Bas Teusink nature.com/articles/s4139…

Structure of c-di-AMP bound to the KdpD-USP domain ... sciencedirect.com/science/articl…

Interesting study on Enterococcus faecalis c-di-AMP signalling - especially when exogenously added c-di-AMP rescues the growth defect of a cdaA mutant. Is c-di-AMP a 'first messenger' also? 🤔

A very useful set of learning resources on food safety of fresh produce

Complex structure of the Bacillus subtilis CdaA c-di-AMP cyclase domain and the phosphoglucomutase GlmM biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage d... sciencedirect.com/science/articl…

BREAKING: Brisbane, Queensland has officially been named the host city for the 2032 Olympic and Paralympic Games. #Brisbane2032

Happy to share our review of cyclic-di-AMP signalling in lactic acid bacteria as part of the LAB symposium special edition in FEMS Thanks to Huong Pham Esteban Marcellin Zhao-Xun Liang & Yuwei for your contributions and many years of collaboration academic.oup.com/femsre/article…

Interesting study on how #cyclicdiamp affects B-lactam resistance in Streptococcus