Hurray! First paper of the TrowitzschLab out now in Nature Communications. A big thank you to everyone involved in this exciting contribution. rdcu.be/cyAT5

Happy to share our work on the cryo-EM structure of human tRNA splicing endonuclease TSEN bound to substrate (biorxiv.org/cgi/content/sh…). Our reconstruction helps rationalize mutants that lead to pontocerebellar hypoplasia. A big 'thank you' to everyone involved in this study!

Congratulations to Ines Müller and all others involved in this beautiful crystallographic work on a transient MHC-I chaperone complex published in Nature Communications! rdcu.be/cVyWI 👍

It is finally out! Our cryo-EM structure of human TSEN in complex with pre-tRNA was just published in NSMB rdcu.be/ddBJH! Flattered to see the News&Views article by Anita Hopper & Jinwei Zhang rdcu.be/ddBJd! Thanks to everyone involved!

change.org/p/nein-zur-elt…

Check out our fresh review on TSEN biology brought together by the Hayne Lab, @RobinStanleyLab, Simon Trowitzsch, and van Hoof Lab now available at JBC jbc.org/article/S0021-…!