Tobias Milzarek
@tobiasmilzarek
Senior Scientist at Laboratory for Natural Product Biotechnology @Helmholtz_HIPS #catalysis #naturalproducts
ID: 1484207839203586051
20-01-2022 16:55:16
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Bis(trifluoromethylated) ethynyl benziodoxoles are useful reagents, yet their synthesis is cumbersome: now Nieves Nieves P. Ramirez , Tobias Tobias Milzarek and Xingyu Xingyu Liu 刘星宇 developed a practical one-pot protocol directly from iodine(I) Chemical Communications pubs.rsc.org/en/content/art…
Interested in the latest Communications? Read 'One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine(i) precursors' by Tobias Milzarek, Nieves P. Ramirez, Xingyu Liu 刘星宇, Waser Group EPFL Chemistry NCCR Catalysis buff.ly/3SrgNxQ
In case you missed it: 'One-pot synthesis of functionalized bis(trifluoromethylated)benziodoxoles from iodine(i) precursors' by Tobias Milzarek, Nieves P. Ramirez, Xingyu Liu 刘星宇, Waser Group EPFL Chemistry NCCR Catalysis bit.ly/45XWNWF bit.ly/45XWNWF
Our most recent work on sorbicillinoid synthesis now online Communications Chemistry - great work by @J_I_Mueller at TU Dresden @TUD_Science and Antibiotikaforschung (inaktiv) Helmholtz-Zentrum für Infektionsforschung –inaktiv. It took a while to develop, but resulted in a super efficient chemo-enzymatic route: link.springer.com/article/10.103…
One last position for a PhD Waser Group to start between August 2024 and January 2025 is now available for a collaborative catalysis project. If you are interested hurry up, as the application process will close on May 15, 2024. More information at: epfl.ch/labs/lcso/grou…
From ChemRxiv to Org. Lett. J Org Chem/Org Lett the work of Diana Diana Cavalli EPFL Chemistry NCCR Catalysis on the synthesis of lactones via an organic-dye catalyzed alkynylative cyclization is now published in its final form pubs.acs.org/doi/10.1021/ac…
What happens when you irradiate carbonyl cyclopropanes with light? The outcome depend on the substrate, but always via a biradical: if you are curious look at the preprint ChemRxiv of Tin Tin V.T. Nguyen André André Bossonnet Duncan Duncan Brownsey and Matt go.shr.lc/3WQAdyb
It is out! Elusive sigma-type cyclopropenium equivalents accessed via a new hypervalent iodine reagent (CpBX), and gold-catalyzed reactions thanks to the huge work of Xiangdong Xiangdong Li with computation from Mat Matthew Wodrich now in Nature Chemistry rdcu.be/dIMlC
Have a look at the work of Vladyslav Vladyslav Smyrnov on accessing cyclopropeniums via a radical-polar crossover approach in Angewandte Chemie . Our work complete recent breakthroughs of Marcos García Suero and SMWH Lab to make cyclopropeniums more accessible. onlinelibrary.wiley.com/doi/10.1002/an…
Xingyu Xingyu Liu 刘星宇 with the help of Olha and Adriana @adriana_faraone developed new non-natural amino acids containing a EBx reagent for solid and solution phase peptide synthesis, leading to new ways towards macrocycles, now accepted Angewandte Chemie onlinelibrary.wiley.com/doi/10.1002/an…
This project was one long and winding road to go, but also lots of fun to solve all the challenging puzzles that came along the way! Enjoy the read of our new article, now published in #JACS! Huge thanks goes out to Katha, JSK, Basti, Ivana, Tilo and TAMGulderLab_TechBioDD!
A big one out from our lab - combining synthesis and enzymology to look in detail into BVMO product selectivity! Very proud of team TAMGulderLab_TechBioDD with Manuel Einsiedler in the lead. Work done Antibiotikaforschung (inaktiv) Helmholtz-Zentrum für Infektionsforschung –inaktiv TU Dresden @TUD_Science J. Am. Chem. Soc. pubs.acs.org/doi/full/10.10…
Our first gut microbiome study: cytotoxic effects of bacillamides! Great work by @Maxxter5 with super collaboration with Markus Tschurtschenthaler @SieberLab Clavellab Valentina Brunner KP Janßen and many others Microbiome Signatures. Antibiotikaforschung (inaktiv) Helmholtz-Zentrum für Infektionsforschung –inaktiv @TUD_Science link.springer.com/article/10.103…
This was a perfect start into the new year with two nice PoTeM stories: doi.org/10.1002/bit.28… doi.org/10.1186/s12934… Lots of effort now finally paid off! Congratulations Anna, Julia and Basti! TAMGulderLab_TechBioDD TU Dresden Helmholtz-Zentrum für Infektionsforschung –inaktiv
Happy to see my first publication of year about the fungal natural product class of sorbicillinoids in Nat. Prod. Reports 🥳 many thanks to the Sorbi team including Anna Manuel Einsiedler @J_I_Mueller 🤗 pubs.rsc.org/en/content/art…
🔓Read this #OpenAccess review by Tobias Milzarek & our Editorial Board Chair Tobias Gulder ToGuLab at Antibiotikaforschung (inaktiv) in our latest issue looking at the structures, bioactivities, biosynthesis & synthesis of the fungal sorbicillinoids Find it below👇 pubs.rsc.org/en/content/art…
A beauty put together by our Tobias Milzarek Antibiotikaforschung (inaktiv) Helmholtz-Zentrum für Infektionsforschung –inaktiv. It summarizes a huge body of work by many on one of our favorite natural product classes, the sorbicillinoids! Thanks to DFG public | @[email protected] for funding!