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New tricks of TALEs! Lebar et al. from @Kemijski show an amazing ability of TALE proteins to displace other TALEs from DNA and use polarized displacement to encode logic functions in mammalian cells and protect #CRISPR cleavage. goo.gl/CDaLQF goo.gl/AAACwz

Animation on the discovery of TALE displacement as a new tool for #synthetic biology to regulate gene expression, design logic functions and prevent offtarget #CRISPR cleavage. Just published online in Nature Chemical Biology goo.gl/AAACwz

🔬 Nov teden, nova gostujoča znanstvenica! V naši rubriki #zManost bo z zanimivimi objavami sodelovala dr. Tina Lebar s Kemijski inštitut!

Happy to have contributed to this work during my time at Kemijski inštitut in the Roman Jerala lab. We designed novel chemically-inducible dimerization systems for mammalian cells. Congrats to all co-authors nature.com/articles/s4158…