We just hosted our 2025 Progress Update toward radically extending human healthspan! x.com/i/broadcasts/1…

The piece of b2b startup advice I find myself giving over and over again recently is figure out how your product can make a *significant* difference in the success of your customer’s business - whether that is driving significant revenue, huge improvements in their customer

Our VP of Engineering, ryandoan will be speaking at the AI Agent Summit at Miami AI Hub this weekend w/ Burhan Sebin on April 5 @ 11AM - If you are a higher ed leader that wants to understand the technical side of how OutRival is creating digital workers to augment the

Llama 4 with 10m (!!!!) context window released! Elo is insane

Learned a lot from my fellow panelists lou mata , ryandoan , Garrett Rowe. So lucky to share the stage with amazing people. Miami AI Hub CrewAI

This week's Uncapped guest is Garry Tan. We discussed why he's able to run YC like a founder, how he picks founders, AI and hard tech, and (obviously) a little bit about the government. Garry is as real as it gets and I learn a ton from him every time we chat.

Just in case you thought we forgot about family

The sweet sweet moment you find product market fit (wait for it)

Excited to announce that Metaplanet has established our U.S. headquarters in Miami. Thank you @francissuarez for the warm welcome. We’re proud to be building in one of the world’s most tech-forward, pro-innovation cities for Bitcoin.

Nice - my AI startup school talk is now up! Chapters: 0:00 Imo fair to say that software is changing quite fundamentally again. LLMs are a new kind of computer, and you program them *in English*. Hence I think they are well deserving of a major version upgrade in terms of

Grok 4 – the facts - Musk wasn't lying, Grok 4 is the best AI model out there - Grok 4 is smarter than all graduate students out there - 100x more training than Grok 2, 10x more RL than any other company for their model - “Post-graduate level at everything” - 44.4% in Humanitys

Florida just became ground zero for the future of medicine. Fountain Life and Celularity Inc. (NASDAQ:CELU) are launching stem cell therapies that beyond treating, will transform health itself. Backed by Florida’s bold new law, we’re rewriting healthcare rules alongside Tony Robbins,

1/N I’m excited to share that our latest OpenAI experimental reasoning LLM has achieved a longstanding grand challenge in AI: gold medal-level performance on the world’s most prestigious math competition—the International Math Olympiad (IMO).

Today, we at OpenAI achieved a milestone that many considered years away: gold medal-level performance on the 2025 IMO with a general reasoning LLM—under the same time limits as humans, without tools. As remarkable as that sounds, it’s even more significant than the headline 🧵

There are multiple reasons why AI coding agents have taken off. But one of them is that the builders of agents are engineers and know exactly what their workflows are. The closer you understand the process, the more you can automate it. You can apply this to any category.

We released two open-weight reasoning models—gpt-oss-120b and gpt-oss-20b—under an Apache 2.0 license. Developed with open-source community feedback, these models deliver meaningful advancements in both reasoning capabilities & safety. openai.com/index/introduc…

Really enjoyed spending time with other founders in the Initialized Capital portfolio that are also building AI Agents. If America wants to win in AI, we can’t just invest in infrastructure and chips...we need to lead in talent and education too. That means empowering the universities