After a lively poster session, we continue with Ping He at #CRC1101 symposium. He will talk about „protein homeostasis, polymerization and condensates“

!!! “Efficient scar-free knock-ins of several kilobases in plants by engineered CRISPR/Cas endonucleases” cell.com/molecular-plan…

Finally online! Efficient HDR in plants by engineered CRISPR-endonucleases! Big Thanks to all involved! 🎉 doi.org/10.1016/j.molp…

The one thing I cannot stand in this world is when people refer to Nicotiana benthamiana as tobacco. It's just benthi, people. kamounlab.medium.com/benthamiana-rh…

LORE receptor homomerization is required for 3‐hydroxydecanoic acid‐induced immune signaling and determines the natural variation of immunosensitivity within the Arabidopsis genus - Eschrig - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/np…

Yes. sciencedirect.com/science/articl…

Out on bioRxiv since last August and now online in peer-reviewed version, a tour de force project by first author Neftaly Cruz Mireles with amazing proteomics support from Paul_D. Very proud of this great collaboration with Nick Talbot from The Sainsbury Laboratory 🧵

It was a true joy to host Thorsten Nürnberger today as postdoc invited speaker at The Sainsbury Laboratory ! So many exciting things happening on plant PRR activation and signaling 🌱✨. Thank you for visiting Norwich!

Receptor-like cytoplasmic kinases of different subfamilies differentially regulate SOBIR1/BAK1-mediated immune responses in Nicotiana benthamiana nature.com/articles/s4146…

Thanks to Thorsten Nürnberger Simon Williams, Natsumi Maruta (UQ) and Chih-Hang Wu for sharing their exciting and partly unpublished data with us at the #IPMB2024 Disease resistance I session. Stay tunes for session II on Thursday 10:20 room 9 chaired by Peter Dodds

Nature research paper: Zinc mediates control of nitrogen fixation via transcription factor filamentation go.nature.com/3ziP9M9

Very proud to share this paper in Nature today. nature.com/articles/s4158… A screen that lead to a completely unexpected regulatory mechanism linking soil nitrogen to the function of legume nodules. A great collaboration with Jieshun Lin Peter Bjørk Marie, Kasper and many others

Please don’t tell my students not to use chatGPT you freakin’ dinosaurs 🦕 🦖 🤡

Yesss! The art of football has won! Congratulations 🇪🇸

I am coming back from a superb visit to ZMBP Tübingen on the train. Many thanks to El Kasmi Lab and Isabel Monte for being my hosts. It was my first visit to ZMBP, and I am deeply impressed by the structure of this research center. It provides unique support to

The plant immune system relies on germline-encoded pattern recognition receptors (PRRs) that sense foreign and plant-derived molecular patterns, and signal health threats

Genomic and pangenomic data sets provide valuable insights into the evolution of PRRs and their molecular triggers, which is furthering our understanding of plant–pathogen co-evolution and convergent evolution

Moreover, in silico and in vivo methods of PRR identification have accelerated the characterization of receptor–ligand complexes, and advances in protein structure prediction algorithms are revealing novel PRR sensor functions

Harnessing recent advances to engineer PRRs presents an opportunity to enhance plant disease resistance against a broad spectrum of pathogens, enabling more sustainable agricultural practices

This Review summarizes both established and innovative approaches to leverage genomic data and translate resulting evolutionary insights into engineering PRR recognition specificities